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Simultaneous Determination of Ten Active Compounds in the Whole Plant of Sarcandra glabra and its Related Traditional Chinese Medicinal Preparations by Ultra High Performance Liquid Chromatography

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收录情况: ◇ SCIE

机构: [1]Second Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine, Guangzhou, P.R. China [2]College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, P.R. China
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关键词: Sarcandra glabra Phenolic compounds UPLC Determination

摘要:
A simple, senstive and specific ultra high performance liquid chromatography (UPLC) was established for the simultaneous determination of ten active compounds in Sarcandra glabra and its preparations e.g., Qingrexiaoyanning capsule, Zhongjiefeng tablet, Xiekang capsule, Jinsulan liniment and Zhongjiefeng injection. The analysis was performed on acquity UPLC system with aquity UPLC BEH C-18 column (50 mm x 2.1 mm I.D., 1.7 mu m) and gradient elution of acetonitrile and water containing 0.1 % formic acid, and all ten major compounds achieved complete separation. Results indicate that the developed UPLC assay can be successfully utilized as a quality method for simultaneous determination of ten representative compounds in Sarcandra global and its related preparations.

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出版当年[2011]版:
大类 | 4 区 化学
小类 | 4 区 化学综合
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出版当年[2010]版:
Q4 CHEMISTRY, MULTIDISCIPLINARY
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影响因子: 最新[2023版] 最新五年平均 出版当年[2010版] 出版当年五年平均 出版前一年[2009版] 出版后一年[2011版]

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第一作者机构: [1]Second Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine, Guangzhou, P.R. China
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