机构：[1]The First Clinical Medical College, Southern Medical University, Guangzhou, Guangdong 510515, People’s Republic of China.[2]Department of Radiology,Foshan Hospital of Traditional Chinese Medicine, Foshan, Guangdong 510515, P.R. China.[3]Department of Radiology, Dehongzhou People’s Hospital, Dehongzhou, Yunan 678400, P.R. China.[4]Department of PET/CT Center, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510000, P.R. China.[5]Department of Medical Imaging, Nanfang Hospital, Southern Medical University, No. 1838 Guangzhou Avenue North, Guangzhou, Guangzhou, Guangdong 510515, P.R. China.
To analyze the features of CT, MRI and PET/CT and their diagnostic value for spinal osteoblastomas (OBs).
The radiological and clinical data of 21 patients with histopathologically-confirmed spinal OBs were analyzed retrospectively.
Sixteen of the 21 cases were benign and 5 were aggressive OBs. Tumors were located in the lumbar (n = 11), cervical (n = 4), thoracic (n = 5), and sacral (n = 1) spinal regions. Nineteen cases were centered in the posterior elements of the spine, 13 of which extended into the vertebral body. Punctate or nodular calcifications were found in all cases on CT with a complete sclerotic rim (n = 12) or incomplete sclerotic rim (n = 8). The flare phenomenon (indicative of surrounding tissue inflammation) was found in 17/21 cases on CT, thin in 11 cases and thick in 6 cases, and in 19/19 cases on MRI, thin in 1 case and thick in 18 cases. On 18F-FDG PET/CT, all cases (8/8) were metabolically active with the SUVmax of 12.3-16.0; the flare sign was observed in 8 cases, including 7 cases of hypometabolism and 1 case of coexistence of hypermetabolism and hypometabolism. Based on CT, 3, 12, and 6 cases were classified as Enneking stage 1, 2 and 3, respectively. Of 19 cases with MRI, 1 and 18 cases were classified as Enneking stage 2 and 3, respectively.
Spinal OB has multiple unique characteristic radiological features. Although a larger sample size is needed, combining CT, MRI and PET may be beneficial to optimize preoperative diagnosis and care of patients with OBs.
基金：
This study was suppoted by the following funds:
Natural Science Foundation of Guangdong Province, China (grant No.
S201301005689)
Science and Technology Program of Guangzhou, China (grant No.
201707010003)
Specical Foundation of President of Nanfang Hospital, Southern Medical
University (grant No. 2016B026)
Scientific Research Initiation Programme of Southern Medical University
(grant No. CX2018N017)
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2019]版：
大类|4 区医学
小类|4 区骨科4 区风湿病学
最新[2025]版：
大类|3 区医学
小类|3 区骨科3 区风湿病学
第一作者：
第一作者机构：[1]The First Clinical Medical College, Southern Medical University, Guangzhou, Guangdong 510515, People’s Republic of China.
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Zihuan Huang,Tingsong Fang,Zhiguang Si,et al.Imaging algorithm and multimodality evaluation of spinal osteoblastoma.[J].BMC musculoskeletal disorders.2020,21(1):240.doi:10.1186/s12891-020-03252-y.
APA：
Zihuan Huang,Tingsong Fang,Zhiguang Si,Youcai Li,Lan Zhang...&Yuankui Wu.(2020).Imaging algorithm and multimodality evaluation of spinal osteoblastoma..BMC musculoskeletal disorders,21,(1)
MLA：
Zihuan Huang,et al."Imaging algorithm and multimodality evaluation of spinal osteoblastoma.".BMC musculoskeletal disorders 21..1(2020):240
