机构：[1]Department of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China[2]Institute of Clinical Anatomy, School of Basic Medical Sciences, Southern Medical University, Guangdong, Guangzhou 510515, China[3]Department of Acupuncture and Rehabilitation, The First Teaching Hospital, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China[4]Radiology Department, West China Hospital of Sichuan University, Chengdu 600075, China四川大学华西医院[5]Life Sciences Research Center, School of Life Sciences and Technology, Xidian University, Xi'an 710071, China[6]China Academy of Chinese Medical Sciences, World Federation of Acupuncture-Moxibustion Societies, Beijing 100061, China
To determine differences in cerebral activity evoked by acupuncture and conventional stroke treatment, and identify the treatment targets.
In total, 21 patients were randomly divided into two groups. Group A (11 patients) received both acupuncture and conventional treatment, while group B (10 patients) received conventional treatment only. Resting-state functional magnetic resonance imaging (fMRI) was performed on each participant before and after treatment. Regional homogeneity analysis was performed to investigate the potential mechanism of acupuncture treatment by comparing differences in cerebral activity between treatments.
Group A showed higher ReHo in the frontal lobe (BA6, BA46), supra-marginal gyrus (BA40), middle temporal gyrus (BA21), cerebellum, and insula. Group B showed higher ReHo in the frontal lobe (BA6) and parietal lobe (BA3, BA7).
Acupuncture and conventional treatment triggered relatively different clinical efficacy and brain responses. Acupuncture treatment more significantly improved the symptoms of stroke patients. More marked changes in sensory, emotional, and motor areas (including the frontal lobe, middle temporal gyrus, cerebellum, and insula) might reflect the specific acupuncture mechanism.
基金：
Supported by the National Natural Science Foundation of
China (NSFC): Acupoint Sensitization Research (No.
81590950); the State Key Program for Basic Research of China:
Clinical Evaluation of the Basic Rules of Acupoint Specification
and Basic Biological Study on CNS Targeting Integration
(No. 2012CB518501); and NSFC: Study on the CNS Integration
Mechanism of Spine-dredging Technique in Treating
Ischemia Stroke (No. 81072864)
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2016]版：
大类|4 区医学
小类|4 区全科医学与补充医学
最新[2025]版：
大类|4 区医学
小类|4 区全科医学与补充医学
第一作者：
第一作者机构：[1]Department of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China
通讯作者：
通讯机构：[1]Department of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China[*1]Department of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
推荐引用方式(GB/T 7714)：
Wu Ping,Zeng Fang,Li Yongxin,et al.Effect of acupuncture plus conventional treatment on brain activity in ischemic stroke patients: a regional homogeneity analysis.[J].Journal of Traditional Chinese Medicine.2017,37(5):650-658.
APA：
Wu Ping,Zeng Fang,Li Yongxin,Li Ji,Qiu Lihua...&Liang Fanrong.(2017).Effect of acupuncture plus conventional treatment on brain activity in ischemic stroke patients: a regional homogeneity analysis..Journal of Traditional Chinese Medicine,37,(5)
MLA：
Wu Ping,et al."Effect of acupuncture plus conventional treatment on brain activity in ischemic stroke patients: a regional homogeneity analysis.".Journal of Traditional Chinese Medicine 37..5(2017):650-658
