机构:[1]Department of Ophthalmology, Xiangya Hospital, Central South University, Changsha, China.[2]Department of Anatomy, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.[3]Department of Ophthalmology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.[4]The State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong, China.[5]GHM Institute of CNS Regeneration, and Guangdong Key Laboratory of Brain Function and Diseases, Jinan University, Guangzhou, China.[6]School of Chinese Medicine, Research Center of Heart, Brain, Hormone and Healthy Aging, The University of Hong Kong, Hong Kong, China.
Adult neurogenesis is an important therapeutic target in treating neurological disorders. Adult neurogenesis takes place in two regions of the brain: Subventricular zone and dentate gyrus in the hippocampus. The progressive understanding on hippocampal neurogenesis in aging and mood disorders increases the demand to explore powerful and subtle interventions on hippocampal neurogenesis. Traditional Chinese herbal medicine provides an abundant pharmaceutical platform for modulating hippocampal neurogenesis. Recent progress in exploring the effects of Chinese herbal medicine and the related mechanisms opens a new direction for regeneration therapy. The current review gives a thorough summary of the research progress made in traditional Chinese herbal formulas, and the effective compounds in Chinese herbs which are beneficial on hippocampal neurogenesis and the possible mechanisms involved.
基金:
Fundamental Research Funds for the
Central Universities (21609101, K. F. So).
语种:
外文
PubmedID:
中科院(CAS)分区:
出版当年[2013]版:
无
最新[2025]版:
大类|3 区医学
小类|3 区全科医学与补充医学
第一作者:
第一作者机构:[1]Department of Ophthalmology, Xiangya Hospital, Central South University, Changsha, China.[2]Department of Anatomy, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.
通讯作者:
通讯机构:[2]Department of Anatomy, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.[3]Department of Ophthalmology, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.[4]The State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong, China.[5]GHM Institute of CNS Regeneration, and Guangdong Key Laboratory of Brain Function and Diseases, Jinan University, Guangzhou, China.[*1]Department of Anatomy, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.
推荐引用方式(GB/T 7714):
Zhang Endong,Shen Jiangang,So Kwok Fai.Chinese traditional medicine and adult neurogenesis in the hippocampus.[J].Journal of traditional and complementary medicine.2014,4(2):77-81.doi:10.4103/2225-4110.130372.
APA:
Zhang Endong,Shen Jiangang&So Kwok Fai.(2014).Chinese traditional medicine and adult neurogenesis in the hippocampus..Journal of traditional and complementary medicine,4,(2)
MLA:
Zhang Endong,et al."Chinese traditional medicine and adult neurogenesis in the hippocampus.".Journal of traditional and complementary medicine 4..2(2014):77-81