机构：[1]Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Science, Southern Medical University, Guangzhou 510515, China[2]State Key Laboratory for Quality Research of Chinese Medicines, Macau University of Science and Technology, Taipa, Macau, China[3]The Center for Disease Control and Prevention of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang 830002, China[4]Cancer Therapeutics Program, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA[5]Oxford Transplant Centre, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Old Road, Headington, Oxford OX3 7LE, United Kingdom[6]Key Laboratory of Orthopaedics and Traumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, The First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China
This work was supported by the Natural Science Foundation of
Guangdong Province, China (No. 2018A030313405), the Science and
Technology Planning Project of Guangdong Province, China (No.
2017A050501020) and the Medical Scientific Research Foundation of
Guangdong Province, China (No. A2018189).
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2019]版：
大类|3 区医学
小类|3 区生化与分子生物学3 区药物化学3 区有机化学
最新[2025]版：
大类|3 区医学
小类|2 区有机化学3 区生化与分子生物学3 区药物化学
第一作者：
第一作者机构：[1]Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Science, Southern Medical University, Guangzhou 510515, China[6]Key Laboratory of Orthopaedics and Traumatology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, The First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Tian Nannan,Wu Huanxian,Zhang Huiwu,et al.Discovery of [1,2,4]triazolo[4,3-a]pyridines as potent Smoothened inhibitors targeting the Hedgehog pathway with improved antitumor activity in vivo.[J].Bioorganic & medicinal chemistry.2020,28(16):115584.doi:10.1016/j.bmc.2020.115584.
APA：
Tian Nannan,Wu Huanxian,Zhang Huiwu,Yang Danni,Lv Lin...&Wu Shaoyu.(2020).Discovery of [1,2,4]triazolo[4,3-a]pyridines as potent Smoothened inhibitors targeting the Hedgehog pathway with improved antitumor activity in vivo..Bioorganic & medicinal chemistry,28,(16)
MLA：
Tian Nannan,et al."Discovery of [1,2,4]triazolo[4,3-a]pyridines as potent Smoothened inhibitors targeting the Hedgehog pathway with improved antitumor activity in vivo.".Bioorganic & medicinal chemistry 28..16(2020):115584
