详情页 - 广东省中医院知识库

当前位置：首页 > 详情页

Mechanisms and Functions of Mitophagy and Potential Roles in Renal Disease.

文献详情

资源类型：

Pubmed体系：

作者：

机构： [1]Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China, [2]Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China, [3]Key Laboratory of Chinese Internal Medicine, Ministry of Education and Beijing, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, China, [4]Renal Research Institution of Beijing University of Chinese Medicine, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, China

出处：

DOI：

ISSN：

关键词： mitophagy mitochondrial dysfunction acute kidney injury diabetic kidney disease lupus nephritis

摘要：

Mitophagy is an evolutionarily conserved process to selectively remove damaged or unnecessary mitochondria via the autophagic machinery. In this review, we focus on recent advances in the molecular mechanisms of mitophagy and how mitophagy contributes to cellular homeostasis in physiological and pathological contexts. We also briefly review and discuss the crosstalk between mitophagy and renal disease, highlighting its modulation as a potentially effective therapeutic strategy to treat kidney diseases such as acute kidney injury (AKI), diabetic kidney disease (DKD), and lupus nephritis (LN). Copyright © 2020 Zuo, Jing, Wu, Wang, Ye, Li, Yang, Pan, Liu and Liu.

基金：

语种：

PubmedID：

中科院(CAS)分区：

出版当年[2019]版：

大类 | 2 区医学

小类 | 2 区生理学

最新[2025]版：

大类 | 3 区医学

小类 | 2 区生理学

第一作者：

第一作者机构： [1]Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China,

共同第一作者：

通讯作者：

通讯机构： [1]Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China, [2]Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China, [3]Key Laboratory of Chinese Internal Medicine, Ministry of Education and Beijing, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, China, [4]Renal Research Institution of Beijing University of Chinese Medicine, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, China

推荐引用方式(GB/T 7714)：

APA：

MLA：

相关文献

[1]Melatonin attenuates sepsis-induced acute kidney injury by promoting mitophagy through SIRT3-mediated TFAM deacetylation [2]Phytochemicals: Targeting Mitophagy to Treat Metabolic Disorders [3]Astragaloside II Ameliorated Podocyte Injury and Mitochondrial Dysfunction in Streptozotocin-Induced Diabetic Rats [4]Absolute quantification and characterization of oxylipins in lupus nephritis and systemic lupus erythematosus [5]Mitophagy in Hepatic Insulin Resistance: Therapeutic Potential and Concerns [6]ADIPOQ rs2241766 Gene Polymorphism and Predisposition to Diabetic Kidney Disease [7]Lysosomal dysfunction-induced autophagic stress in diabetic kidney disease. [8]Niclosamide ethanolamine improves diabetes and diabetic kidney disease in mice. [9]狼疮性肾炎肾组织凋亡及凋亡相关蛋白Survivin的表达 [10]Predicting in-hospital outcomes of patients with acute kidney injury