机构：[1]Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, No.58 Zhongshan Road 2, Guangzhou 510080, China.中山大学附属第一医院[2]Department of Neurology, First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, Guangxi, China.
Cervicocerebral artery dissection is an important cause of ischemic stroke in young and middle-aged individuals. However, very few studies have compared the differential features between internal carotid artery dissection (ICAD) and vertebral artery dissection (VAD), including both cervical and intracranial artery dissections. We conducted a study to investigate the predisposing factors and radiological features in patients with ICAD or VAD.
All cases diagnosed with cervicocerebral artery dissection, ICAD, or VAD were identified through a medical records database, between January 2010 and January 2020. Baseline characteristics, predisposing factors, and radiological features of ICAD versus VAD were compared.
A total of 140 patients with cervicocerebral artery dissection were included in the study, including 84 patients in the ICAD group and 56 in the VAD group. The mean age of patients in the ICAD and VAD groups was 43.37 ± 14.01 and 41.00 ± 12.98 years old, respectively. Patients with ICAD were more likely to be men compared with VAD (85.71% vs. 67.86%, p = 0.012). The frequency of hypertension, diabetes, smoking, drinking, and cervical trauma did not differ between ICAD and VAD. Dissections of ICAD were more frequently at the extracranial portions of the artery compared with those of VAD (70.24% vs. 44.64%, p = 0.003). In contrast, dissections of VAD were more common in the intracranial artery (55.36% vs. 29.76%, p = 0.003). Radiologically, double lumen (36.90% vs. 19.64%, p = 0.029) and intimal flap (11.90% vs. 1.79%, p = 0.029) were more frequently observed in ICAD than in VAD, and dissecting aneurysms were less frequent (13.10% vs. 26.79%, p = 0.041).
The distributions of cervical and intracranial artery dissections were different between ICAD and VAD. The frequencies of radiological features detected in patients with ICAD and VAD also differed.
基金：
This study was supported by grants from National Key R&D Program of
China (2017YFC1307500), the Natural Science Foundation of Guangdong
province of China (2017A030313575, 2017A030310523), the Medical Science
Foundation of Guangdong Province of China (A2016268), the Scientific and
Technical Project of Guangdong Province (2019A030317006), Sun Yat-sen
University Clinical Research 5010 Program (2018001), the Southern China
International Cooperation Base for Early Intervention and Functional Rehabilitation
of Neurological Diseases (2015B050501003), Guangdong Provincial Engineering
Center For Major Neurological Disease Treatment, Guangdong
Provincial Translational Medicine Innovation Platform for Diagnosis and Treatment
of Major Neurological Disease, Guangdong Provincial Clinical Research
Center for Neurological Diseases.
第一作者机构：[1]Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, No.58 Zhongshan Road 2, Guangzhou 510080, China.[2]Department of Neurology, First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, Guangxi, China.
共同第一作者：
通讯作者：
推荐引用方式(GB/T 7714)：
Yongjun Wu,Hongbin Chen,Shihui Xing,et al.Predisposing factors and radiological features in patients with internal carotid artery dissection or vertebral artery dissection.[J].BMC NEUROLOGY.2020,20(1):doi:10.1186/s12883-020-02020-8.
APA：
Yongjun Wu,Hongbin Chen,Shihui Xing,Shuangquan Tan,Xinran Chen...&Jian Zhang.(2020).Predisposing factors and radiological features in patients with internal carotid artery dissection or vertebral artery dissection..BMC NEUROLOGY,20,(1)
MLA：
Yongjun Wu,et al."Predisposing factors and radiological features in patients with internal carotid artery dissection or vertebral artery dissection.".BMC NEUROLOGY 20..1(2020)
