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Clinical study of a 125I particle-integrated esophageal covered stent and hyperbaric oxygen in the treatment of advanced esophageal cancer.

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机构: [1]Department of Oncology. Guangdong TCM-Integrated Hospital. Foshan. China. [2]Department of Oncology. Wuyi Hospital of Traditional Chinese medicine. Jiangmen . China. [3]Department of Intervention. The First Affiliated Hospital of Guangzhou Medical University. Guangzhou. China. [4]Department of Oncology. Gaoming People's Hospital. Gaoming. China.
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关键词: 125I radioactive seeds Coated stent Hyperbaric oxygen Squamous cell carcinomas

摘要:
This study aimed to investigate the clinical efficacy and feasibility of the treatment of advanced esophageal cancer with a combination of a 125I particle-integrated esophageal covered stent and hyperbaric oxygen. 45 patients with advanced esophageal cancer were enrolled and were randomly divided into two groups: a treatment group and a control group. Patients in the treatment group were treated with a 125I particle-integrated esophageal covered stent and hyperbaric oxygen, while patients in the control group were treated with a 125I particle-integrated esophageal covered stent, and the clinical effects and long-term survival time of the two groups were observed. In the treatment group, the complete remission (CR) rate and partial remission (PR) rate of local lesions were 19.2% and 61.5% respectively, and the total effective rate was 80.7%. In the control group, the CR rate and PR rate of local lesions were 10.5% and 52.6%, respectively, and the total effective rate was 63.1%. The total effective rate was higher in the treatment group than in the control group, and the difference was statistically significant (P < 0.05). The combination of a 125I particle-integrated esophageal covered stent and hyperbaric oxygen shows good short- and long-term efficacy in the treatment of advanced esophageal cancer.

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出版当年[2020]版:
大类 | 4 区 医学
小类 | 4 区 胃肠肝病学
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 胃肠肝病学
第一作者:
第一作者机构: [1]Department of Oncology. Guangdong TCM-Integrated Hospital. Foshan. China. [*1]Department of Oncology, Guangdong TCM-Integrated Hospital, No. 16 of South Fifth Road, Guicheng, Nanhai District, Foshan 528200, China
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通讯作者:
通讯机构: [1]Department of Oncology. Guangdong TCM-Integrated Hospital. Foshan. China. [*1]Department of Oncology, Guangdong TCM-Integrated Hospital, No. 16 of South Fifth Road, Guicheng, Nanhai District, Foshan 528200, China
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