Rescued from desperation: adult-onset Still's disease with life-threatening interstitial lung disease and macrophage activation Successful treatment by Tocilizumab
机构：[1]State Key Laboratory of Quality Research in ChineseMedicine/Macau Institute for Applied Research in Medicine and Health,Macau University of Science and Technology, Macau, China[2]Department of Rheumatology and Immunology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China
This article presents a case of fulminant interstitial lung disease (ILD) with macrophage activation syndrome (MAS) as a rare complication of adult-onset Still's disease in a 43-year-old male patient. Initial presentation showed severe ILD. Early treatment focused on high-dose corticosteroids; however, disease remission could not be achieved. After an additional inflammatory focus and underlying malignancy were excluded, the triad of pancytopenia, fever, and high ferritin levels indicated MAS; bone marrow biopsy confirmed secondary hemophagocytic histiocytosis. Treatment with tocilizumab induced fast and effective therapeutic success.
第一作者机构：[1]State Key Laboratory of Quality Research in ChineseMedicine/Macau Institute for Applied Research in Medicine and Health,Macau University of Science and Technology, Macau, China[2]Department of Rheumatology and Immunology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China
共同第一作者：
通讯作者：
通讯机构：[1]State Key Laboratory of Quality Research in ChineseMedicine/Macau Institute for Applied Research in Medicine and Health,Macau University of Science and Technology, Macau, China[*1]State Key Laboratory of Quality Research in Chinese Medicine/Macau Institute for Applied Research in Medicine and Health, Macau University of Science and Technology 999078 Macau, China
推荐引用方式(GB/T 7714)：
Zhang Guangfeng,Liu Wenxue,Zhang Xiao,et al.Rescued from desperation: adult-onset Still's disease with life-threatening interstitial lung disease and macrophage activation Successful treatment by Tocilizumab[J].ZEITSCHRIFT FUR RHEUMATOLOGIE.2022,81(4):335-338.doi:10.1007/s00393-021-01063-7.
APA：
Zhang, Guangfeng,Liu, Wenxue,Zhang, Xiao&Liu, Liang.(2022).Rescued from desperation: adult-onset Still's disease with life-threatening interstitial lung disease and macrophage activation Successful treatment by Tocilizumab.ZEITSCHRIFT FUR RHEUMATOLOGIE,81,(4)
MLA：
Zhang, Guangfeng,et al."Rescued from desperation: adult-onset Still's disease with life-threatening interstitial lung disease and macrophage activation Successful treatment by Tocilizumab".ZEITSCHRIFT FUR RHEUMATOLOGIE 81..4(2022):335-338
