Multi-criterion decision making-based multi-channel hierarchical fusion of digital breast tomosynthesis and digital mammography for breast mass discrimination
机构:[1]Radiotherapy Center, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, Guangdong, 510095, China[2]School of Biomedical Engineering, Southern Medical University, Guangzhou, Guangdong, 510515, China[3]The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510120, China广东省中医院[4]Department of Radiology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, China
Multifaceted features decoded from mammographic images may describe various perspectives of the breast mass heterogeneity, in this study, we aimed to explore a methodology to effectively integrate multifaceted mass representations extracted from the digital breast tomosynthesis (DBT) and full-field digital mammography (FFDM) to enhance breast cancer discrimination. A novel multi-criterion decision making-based multi-channel fusion (MDMF) framework was proposed to fuse different breast mass representations processed in multi-channels built on the deep convolutional neural network (DCNN) and the multilayer perceptron (MLP) at the decision level. A hierarchical framework (HFMM) was also developed for multi-modality images and multi-channel fusion to integrate multimodality information from DBT and FFDM. We retrospectively collected 441 patients with both DBT and FFDM, and the regions of interest (ROIs) covering the malignant, benign, and normal tissues were extracted for validation. The MDMF achieved the area under the receiver operating characteristic curve (AUC) of 93.14%, 91.30%, 97.35% (FFDM) and 93.79%, 95.16%, 99.31% (DBT) respectively for the malignant, benign and normal mass. While the HFMM further boosted the performance to AUC of malignant 94.14%, benign 95.42% and normal mass 99.56% The matthews correlation coefficient (MCC) were 73.15% and 81.02% for FFDM and DBT accomplished by MDMF, and enhanced to 81.72% when integrating the multimodality information from DBT and FFDM via the proposed HFMM. The experimental results suggested that the proposed HFMM achieved superior discriminative performance when compared with the benchmark classification algorithms and fusion architectures, rendering it a practical tool for breast mass discrimination in breast cancer screening. (C) 2021 Elsevier B.V. All rights reserved.
基金:
National Natural Science
Foundation of China (81874216), the Guangzhou Science and
Technology Plan (202102010264), the Natural Science Foundation
of Guangdong Province (2021A1515011329), and the Medical Scientific
Research Foundation of Guangdong Province (A2021202).
第一作者机构:[1]Radiotherapy Center, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou, Guangdong, 510095, China
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推荐引用方式(GB/T 7714):
Wang Linjing,He Qiang,Wang Xuetao,et al.Multi-criterion decision making-based multi-channel hierarchical fusion of digital breast tomosynthesis and digital mammography for breast mass discrimination[J].KNOWLEDGE-BASED SYSTEMS.2021,228:107303.doi:10.1016/j.knosys.2021.107303.
APA:
Wang, Linjing,He, Qiang,Wang, Xuetao,Song, Ting,Li, Xin...&Zhen, Xin.(2021).Multi-criterion decision making-based multi-channel hierarchical fusion of digital breast tomosynthesis and digital mammography for breast mass discrimination.KNOWLEDGE-BASED SYSTEMS,228,
MLA:
Wang, Linjing,et al."Multi-criterion decision making-based multi-channel hierarchical fusion of digital breast tomosynthesis and digital mammography for breast mass discrimination".KNOWLEDGE-BASED SYSTEMS 228.(2021)