详情页 - 广东省中医院知识库

当前位置：首页 > 详情页

Exosomes as Smart Nanoplatforms for Diagnosis and Therapy of Cancer.

11| 认领 | 导出 | 链接全文 |

文献详情

资源类型：

WOS体系：

Pubmed体系：

收录情况： ◇ SCIE

作者：

机构： [1]Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China [2]Department of Mammary Disease, Guangdong Provincial Hospital of Chinese Medicine, The Second Clinical Collage of Guangzhou University of Chinese Medicine, Guangzhou, China [3]School of Fundamental Medical Science, Guangzhou University of Chinese Medicine, Guangzhou, China [4]State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, China

出处：

DOI：

ISSN：

关键词： exosomes biomarker cancer diagnosis cancer therapy brain cancer

摘要：

Exosomes are composed of a lipid bilayer membrane, containing proteins, nucleic acids, DNA, RNA, etc., derived from donor cells. They have a size range of approximately 30-150 nm. The intrinsic characteristics of exosomes, including efficient cellular uptake, low immunogenicity, low toxicity, intrinsic ability to traverse biological barriers, and inherent targeting ability, facilitate their application to the drug delivery system. Here, we review the generation, uptake, separation, and purification methods of exosomes, focusing on their application as carriers in tumor diagnosis and treatment, especially in brain tumors, as well as the patent applications of exosomes in recent years.Copyright © 2021 Zhao, Liu, Tan, Chen, Wang and Chen.

基金：

语种：

WOS：

PubmedID：

中科院(CAS)分区：

出版当年[2020]版：

大类 | 2 区医学

小类 | 3 区肿瘤学

最新[2025]版：

大类 | 3 区医学

小类 | 4 区肿瘤学

JCR分区：

出版当年[2019]版：

Q2 ONCOLOGY

最新[2023]版：

Q2 ONCOLOGY

影响因子： 3.5 最新[2023版] 4 最新五年平均 4.848 出版当年[2019版] 0 出版当年五年平均 4.137 出版前一年[2018版] 6.244 出版后一年[2020版]

第一作者：

第一作者机构： [1]Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China [2]Department of Mammary Disease, Guangdong Provincial Hospital of Chinese Medicine, The Second Clinical Collage of Guangzhou University of Chinese Medicine, Guangzhou, China

通讯作者：

推荐引用方式(GB/T 7714)：

APA：

MLA：

相关文献

[1]Exosomal CA125 as A Promising Biomarker for Ovarian Cancer Diagnosis. [2]circMSH3 is a potential biomarker for the diagnosis of colorectal cancer and affects the distant metastasis of colorectal cancer [3]Exosomal microRNA Therapy for Non-Small-Cell Lung Cancer [4]Clinical progress of anti-angiogenic targeted therapy and combination therapy for gastric cancer [5]Tumor-Derived Exosomal RNA From Fine-Needle Aspiration Supernatant as a Novel Liquid Biopsy for Molecular Diagnosis of Cancer [6]血清胸苷激酶1在乳腺癌诊治中的应用 [7]Sonodynamic therapy-derived multimodal synergistic cancer therapy. [8]K562细胞分泌exosomes的观察及膜表面标志分子CD63的克隆 [9]不同筛查方法对宫颈癌的诊断价值 [10]Functionalization and cancer-targeting design of ruthenium complexes for precise cancer therapy