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Exosomal microRNA Therapy for Non-Small-Cell Lung Cancer

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机构: [1]Jinan University, Guangzhou, Guangdong, China. [2]Fuda Cancer Hospital Affiliated to Jinan University, Guangzhou, Guangdong, China. [3]Ruikang Hospital, Guangxi University of Chinese Medicine, Nanning, Guangxi, China.
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关键词: exosomes microRNA mRNA signal pathway non-small cell lung cancer (NSCLC)

摘要:
With the progress of molecular diagnosis research on non-small cell lung cancer (NSCLC) cells, four identified categories of microRNAs have been found to be related to disease diagnosis, diagnosis of treatment resistance, prediction of prognosis, and drugs for treatment. To date, nine target mRNA/signal pathways have been confirmed for microRNA drug therapy both in vitro and in vivo. When microRNA drugs enter blood vessels, they target the tumor site and play a similar role to that of targeted drugs. However, whether they will produce serious off-target effects remains unknown, and further clinical research is needed. This review provides the first summary of microRNA therapy for NSCLC.

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出版当年[2022]版:
大类 | 4 区 医学
小类 | 4 区 肿瘤学
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 肿瘤学
第一作者:
第一作者机构: [1]Jinan University, Guangzhou, Guangdong, China. [2]Fuda Cancer Hospital Affiliated to Jinan University, Guangzhou, Guangdong, China. [3]Ruikang Hospital, Guangxi University of Chinese Medicine, Nanning, Guangxi, China.
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通讯作者:
通讯机构: [3]Ruikang Hospital, Guangxi University of Chinese Medicine, Nanning, Guangxi, China. [*1]Ruikang Hospital Affiliated to Guangxi University of Traditional Chinese Medicine, No. 10 of Huadong Road, Xingning District, 530011 Nanning, Guangxi, China.
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