机构：[1]The Second Clinical Medical College, and Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome, Guangzhou University of Chinese Medicine, Guangzhou, China广东省中医院[2]Guangzhou Key Laboratory of Chirality Research on Active Components of Traditional Chinese Medicine, Guangzhou, China[3]College of Basic Medical Science, Guangzhou University of Chinese Medicine, Guangzhou, China[4]Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China[5]State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangzhou, China[6]Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research,Guangzhou University of Chinese Medicine, Guangzhou, China[7]Division of Pharmacognosy, Biomedical Center, Uppsala University, Uppsala, Sweden
K. galanga is an aromatic medicinal herb. It is locally to India and distributed in China, Myanmar, Indonesia, Malaysia, and Thailand. K. galanga is a Traditional Chinese Herb Medicine (TCHM), which has been applied to treat cold, dry cough, toothaches, rheumatism, hypertension and so on. In addition, it has been used widely as spices since its highly aromas. The aim of this review is to compile and update the current progresses of ethnomedicinal uses, phytochemistry, pharmacology and toxicology of K. galanga. All the data on K. galanga were based on different classical literary works, multiple electronic databases including SciFinder, Web of Science, PubMed, etc. The results showed that ninety-seven compounds have been identified from rhizome of K. galanga, including terpenoids, phenolics, cyclic dipeptides, flavonoids, diarylheptanoids, fatty acids and esters. Modern pharmacology studies revealed that extracts or secondary metabolites of the herb possessed anti-inflammatory, anti-oxidant, anti-tumorous, anti-bacterial, and anti-angiogenesis effects, which were closely related to its abundant ethnomedicinal uses. In conclusion, although previous research works have provided various information of K. galanga, more in-depth studies are still necessary to systemically evaluate phytochemistry, pharmacological activities, toxicity and quality control of this herb.</p>
基金：
Key-Area Research and
Development Program of Guangdong Province (No.
2020B1111110007); the National Natural Science Foundation
of China (Nos. 81202398, 81974565, and 81974571); The
special foundation of Guangzhou Key Laboratory (No.
202002010004); Science and Technology Planning Project of
Guangdong Province(No. 2017B030314166); the Specific
Research Project of State Administration of TCM of China
(No. JDZX2015207); Special Funds for State Key Laboratory of
Dampness Syndrome of Chinese Medicine (Nos. SZ2021ZZ33,
SZ2021ZZ36, SZ2021ZZ40, and SZ2021ZZ46); the Specific
Research Fund for TCM Science and Technology of
Guangdong Provincial Hospital of Chinese Medicine (No.
YN2019MJ05) and the collaborative innovation project of
“Double first class” and High-level University Construction of
Guangzhou University of Chinese Medicine (Nos. 2021XK69 and
2021XK08).
第一作者机构：[1]The Second Clinical Medical College, and Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome, Guangzhou University of Chinese Medicine, Guangzhou, China[2]Guangzhou Key Laboratory of Chirality Research on Active Components of Traditional Chinese Medicine, Guangzhou, China
共同第一作者：
通讯作者：
通讯机构：[1]The Second Clinical Medical College, and Guangdong Provincial Key Laboratory of Clinical Research on Traditional Chinese Medicine Syndrome, Guangzhou University of Chinese Medicine, Guangzhou, China[2]Guangzhou Key Laboratory of Chirality Research on Active Components of Traditional Chinese Medicine, Guangzhou, China[5]State Key Laboratory of Dampness Syndrome of Chinese Medicine, Guangzhou, China[6]Guangdong-Hong Kong-Macau Joint Lab on Chinese Medicine and Immune Disease Research,Guangzhou University of Chinese Medicine, Guangzhou, China
推荐引用方式(GB/T 7714)：
Si-Yu Wang,Hui Zhao,Hong-Tao Xu,et al.Kaempferia galanga L.: Progresses in Phytochemistry, Pharmacology, Toxicology and Ethnomedicinal Uses[J].FRONTIERS IN PHARMACOLOGY.2021,12:doi:10.3389/fphar.2021.675350.
APA：
Si-Yu Wang,Hui Zhao,Hong-Tao Xu,Xiao-Dong Han,Yun-Shan Wu...&Bo Liu.(2021).Kaempferia galanga L.: Progresses in Phytochemistry, Pharmacology, Toxicology and Ethnomedicinal Uses.FRONTIERS IN PHARMACOLOGY,12,
MLA：
Si-Yu Wang,et al."Kaempferia galanga L.: Progresses in Phytochemistry, Pharmacology, Toxicology and Ethnomedicinal Uses".FRONTIERS IN PHARMACOLOGY 12.(2021)
