机构：[1]Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Teaching Hospital of Fujian Medical University, Xiamen, China.[2]Pulmonary and Critical Care Medicine, The First Hospital of Longyan Affiliated to Fujian Medical University, Longyan, Fujian, China.[3]Pulmonary and Critical Care Medicine, Second Affiliated Hospital of Fujian Medical University, Respiratory Medicine Center of Fujian Province, Quanzhou, Fujian, China.[4]Pulmonary and Critical Care Medicine, The Second Hospital of Longyan, Longyan, Fujian, China.[5]Pulmonary and Critical Care Medicine, The First Hospital of Putian, Putian, Fujian, China.[6]Pulmonary and Critical Care Medicine, Fuqing Hospital, Fuqing, Fujian, China.[7]Pulmonary and Critical Care Medicine, The Second People's Hospital Affiliated to Fujian Traditional Chinese Medicine, Fuzhou, Fujian, China.[8]Pulmonary and Critical Care Medicine, Chenzhou No. 1 People's Hospital, Chenzhou Hunan, China.[9]Pulmonary and Critical Care Medicine, Maoming People's Hospital, Maoming, Guangdong, Chian.
Pulmonary rehabilitation (PR) is an essential method for Acute exacerbation in chronic obstructive pulmonary disease (AECOPD) recovery. We perform a meta-analysis to compare early PR with usual care. A literature search was performed through these databases: PubMed, MEDLINE database, Google Scholar, Cochrane, Embase from inception to July 2021. Eligible trials were clinical randomized controlled trials comparing the effects of early PR and usual care in AECOPD patients. The primary endpoint of this meta-analysis was FEV1% predicted, 6-min walk test (6MWD), modified Medical Research Council (mMRC) and George Respiratory Questionnaire-total (SGRQ-total). The secondary outcomes were borg dyspnea score, short-form 36 health survey questionnaire physical (SF-36 physical) and SF-36 mental. We included 13 RCTs with a total of 866 patients. There were no significant effects of the PR group on measures of FEV1% predicted (MD = 0.50, 95%CI -1.43 to 2.44, Z = 0.51, p = 0.61), borg dyspnea score (MD = -0.88, 95%CI -1.89 to 0.13, Z = 1.71, p = 0.09) and SF-36 mental (MD = 4.34, 95%CI -1.64 to 10.32, Z = 1.42, p = 0.16) compared with usual care. PR group achieved better 6MWD (MD = 97.58, 95%CI 17.21 to 177.96, Z = 2.38, p = 0.02), mMRC (MD = -0.36, 95%CI -0.52 to -0.21, Z = 4.56, p ˂ 0.00001), SGRQ-total (MD= -9.67, 95%CI -16.23 to -3.11, Z = 2.89, p = 0.004) and SF-36 physical (MD = 4.98, 95%CI 0.60 to 9.35, Z = 2.23, p = 0.03) compared with usual care group. Early PR in AECOPD patients would lead to better 6MWD, mMRC, SGRQ-total and SF-36 physical. But there were no significant effects of the PR group on measures of FEV1% predicted, borg dyspnea score and SF-36 mental.
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外文
PubmedID：
中科院(CAS)分区：
出版当年[2021]版：
大类|4 区医学
小类|4 区呼吸系统
最新[2025]版：
大类|4 区医学
小类|4 区呼吸系统
第一作者：
第一作者机构：[1]Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Teaching Hospital of Fujian Medical University, Xiamen, China.[*1]NO 201-209, Hubin South Road, Siming District, Xiamen, 351004, Fujian Province, People’s Republic of China
共同第一作者：
通讯作者：
通讯机构：[1]Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Teaching Hospital of Fujian Medical University, Xiamen, China.[*1]NO 201-209, Hubin South Road, Siming District, Xiamen, 351004, Fujian Province, People’s Republic of China
推荐引用方式(GB/T 7714)：
Du Yanping,Lin Jun,Wang Xiaoxia,et al.Early Pulmonary Rehabilitation in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Meta-Analysis of Randomized Controlled Trials.[J].COPD.2022,1-12.doi:10.1080/15412555.2022.2029834.
APA：
Du Yanping,Lin Jun,Wang Xiaoxia,Zhang Yan,Ge Hua...&Tan Shifan.(2022).Early Pulmonary Rehabilitation in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Meta-Analysis of Randomized Controlled Trials..COPD,,
MLA：
Du Yanping,et al."Early Pulmonary Rehabilitation in Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Meta-Analysis of Randomized Controlled Trials.".COPD .(2022):1-12
