详情页 - 广东省中医院知识库

当前位置：首页 > 详情页

Current Immunotherapies for Glioblastoma Multiforme.

文献详情

资源类型：

Pubmed体系：

作者：

机构： [1]Department of Neurosurgery, Beijing Electric Power Hospital, Beijing, China, [2]Department of Neurosurgery, Huizhou Third People’s Hospital, Guangzhou Medical University, Huizhou, China, [3]Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Guangzhou, China, [4]Department of Neurosurgery, The First Affiliated Hospital, Jinan University, Guangzhou, China, [5]Department of Neurosurgery, Jiujiang Hospital of Traditional Chinese Medicine, Jiujiang, China

出处：

DOI：

关键词： immunotherapy glioblastoma multiforme glioma vaccines checkpoint inhibitors

摘要：

Glioblastoma multiforme (GBM) is the most common and aggressive malignant tumor found in the central nervous system. Currently, standard treatments in the clinic include maximal safe surgical resection, radiation, and chemotherapy and are mostly limited by low therapeutic efficiency correlated with poor prognosis. Immunotherapy, which predominantly focuses on peptide vaccines, dendritic cell vaccines, chimeric antigen receptor T cells, checkpoint inhibitor therapy, and oncolytic virotherapy, have achieved some promising results in both preclinical and clinical trials. The future of immune therapy for GBM requires an integrated effort with rational combinations of vaccine therapy, cell therapy, and radio- and chemotherapy as well as molecule therapy targeting the tumor microenvironment.Copyright © 2021 Huang, Li, Li, Zhang, Zong and Zhang.

基金：

语种：

PubmedID：

中科院(CAS)分区：

出版当年[2019]版：

大类 | 2 区医学

小类 | 2 区免疫学

最新[2025]版：

大类 | 2 区医学

小类 | 2 区免疫学

第一作者：

第一作者机构： [1]Department of Neurosurgery, Beijing Electric Power Hospital, Beijing, China,

共同第一作者：

通讯作者：

通讯机构： [2]Department of Neurosurgery, Huizhou Third People’s Hospital, Guangzhou Medical University, Huizhou, China, [3]Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, The National Key Clinical Specialty, The Engineering Technology Research Center of Education Ministry of China, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, Guangzhou, China, [5]Department of Neurosurgery, Jiujiang Hospital of Traditional Chinese Medicine, Jiujiang, China

推荐引用方式(GB/T 7714)：

APA：

MLA：

Current Immunotherapies for Glioblastoma Multiforme.

文献详情

相关文献