机构：[1]Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China,[2]School of Second Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, China,[3]TCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China
With the sharp change in our diet and lifestyle, the incidence of colorectal cancer (CRC) is increasing among young people and has become the second most common malignant tumor worldwide. Although the current treatment of CRC is getting updated rapidly, recurrence and metastasis are still inevitable. Therefore, new anticancer drugs are needed to break existing limitations. In recent years, Hedyotis diffusa Willd (HDW) extracts have been proved to demonstrate excellent anti-colorectal cancer effects and have been widely used in clinical practices. In this review, we aim to explore the advantages, potential signaling pathways, and representative active ingredients of HDW in the treatment of CRC from the perspective of molecular mechanism, in order to provide new ideas for the future treatment of CRC.
基金：
National Nature Science Foundation of China [8274315]
第一作者机构：[1]Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China,
通讯作者：
推荐引用方式(GB/T 7714)：
Wu Zihong,Yin Bei,You Fengming.Molecular Mechanism of Anti-Colorectal Cancer Effect of Hedyotis diffusa Willd and Its Extracts[J].FRONTIERS IN PHARMACOLOGY.2022,13:doi:10.3389/fphar.2022.820474.
APA：
Wu, Zihong,Yin, Bei&You, Fengming.(2022).Molecular Mechanism of Anti-Colorectal Cancer Effect of Hedyotis diffusa Willd and Its Extracts.FRONTIERS IN PHARMACOLOGY,13,
MLA：
Wu, Zihong,et al."Molecular Mechanism of Anti-Colorectal Cancer Effect of Hedyotis diffusa Willd and Its Extracts".FRONTIERS IN PHARMACOLOGY 13.(2022)
医学