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Stem cell-derived exosomal transcriptomes for wound healing

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机构: [1]The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China. [2]The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China. [3]National Institute of Stem Cell Clinical Research, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China. [4]Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China. [5]Research and Development Department, Guangzhou Qinglan Biotechnology Company Limited, Guangzhou, China.
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关键词: wound healing stem cell exosome microRNA long noncoding RNA circular RNA messenger RNA

摘要:
Wound healing is a complex and integrated process of the interaction of various components within the injured tissue. Accumulating evidence suggested that stem cell-derived exosomal transcriptomes could serve as key regulatory molecules in wound healing in stem cell therapy. Stem cell-derived exosomal transcriptomes mainly consist of long noncoding RNAs (lncRNAs), microRNAs (miRNAs), circular RNAs (circRNAs) and messenger RNAs (mRNAs). In this article we presented a brief introduction on the wound repair process and exosomal transcriptomes. Meanwhile, we summarized our current knowledge of the involvement of exosomal transcriptomes in physiological and pathological wound repair process including inflammation, angiogenesis, and scar formation.© 2022 Chen, Chen, Zeng and Zhu.

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出版当年[2021]版:
大类 | 3 区 医学
小类 | 3 区 外科
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 外科
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出版当年[2020]版:
Q2 SURGERY
最新[2023]版:
Q2 SURGERY

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第一作者机构: [1]The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China. [2]The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China. [3]National Institute of Stem Cell Clinical Research, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China. [4]Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China.
通讯作者:
通讯机构: [1]The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China. [2]The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China. [3]National Institute of Stem Cell Clinical Research, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China. [4]Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China.
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