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LOX-1 Regulation in Anti-atherosclerosis of Active Compounds of Herbal Medicine: Current Knowledge and the New Insight

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Pubmed体系：

收录情况： ◇ SCIE ◇ 统计源期刊 ◇ CSCD-C ◇ 卓越：梯队期刊

作者：

机构： [1]Guangzhou Univ Chinese Med, State Key Lab Dampness Syndrome Chinese Med, Dept Cardiol, Affiliated Hosp 2, Guangzhou 510020, Peoples R China [2]Guangdong Prov Key Lab Chinese Med Prevent & Trea, Guangzhou 510020, Peoples R China [3]Guangzhou Univ Chinese Med, Clin Med Coll 2, Guangzhou 510405, Peoples R China

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DOI：

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关键词： atherosclerosis herbal medicine lectin-like oxidized low-density lipoprotein receptor-1 targeted therapy

摘要：

Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) have recently been identified to be closely related to the occurrence and development of atherosclerosis (AS). A growing body of evidence has suggested Chinese medicine takes unique advantages in preventing and treating AS. In this review, the related research progress of AS and LOX-1 has been summarized. And the anti-AS effects of 10 active components of herbal medicine through LOX-1 regulation have been further reviewed. As a potential biomarker and target for intervention in AS, LOX-1 targeted therapy might provide a promising and novel approach to atherosclerotic prevention and treatment.

基金：

基金编号： 81874432 82074369 2018B030322012

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中科院(CAS)分区：

出版当年[2022]版：

大类 | 3 区医学

小类 | 3 区全科医学与补充医学

最新[2025]版：

大类 | 4 区医学

小类 | 4 区全科医学与补充医学

JCR分区：

出版当年[2021]版：

Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE

最新[2023]版：

Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE

影响因子： 2.2 最新[2023版] 2.3 最新五年平均 2.626 出版当年[2021版] 2.395 出版当年五年平均 1.978 出版前一年[2020版] 2.9 出版后一年[2022版]

第一作者：

第一作者机构： [1]Guangzhou Univ Chinese Med, State Key Lab Dampness Syndrome Chinese Med, Dept Cardiol, Affiliated Hosp 2, Guangzhou 510020, Peoples R China

通讯作者：

通讯机构： [1]Guangzhou Univ Chinese Med, State Key Lab Dampness Syndrome Chinese Med, Dept Cardiol, Affiliated Hosp 2, Guangzhou 510020, Peoples R China [2]Guangdong Prov Key Lab Chinese Med Prevent & Trea, Guangzhou 510020, Peoples R China [3]Guangzhou Univ Chinese Med, Clin Med Coll 2, Guangzhou 510405, Peoples R China

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