详情页 - 广东省中医院知识库

当前位置：首页 > 详情页

Fatal toxic epidermal necrolysis associated with sinomenine in a patient with primary membranous nephropathy

文献详情

资源类型：

Pubmed体系：

作者：

机构： [1]State Key Laboratory of Quality Research in Chinese Medicine, Macao University of Science and Technology, Macao, and. [2]Department of Nephropathy, Zhuhai Hospital of Integrated Chinese and Western Medicine, Zhuhai, Guangdong, China.

出处：

DOI：

关键词： toxic epidermal necrolysis sinomenine primary membranous nephropathy

摘要：

Sinomenine (SIN), the alkaloid monomer extracted from Sinomenium acutum, is a kind of non-steroidal anti-inflammatory drug widely used in China to treat rheumatoid arthritis (RA) and various glomerular diseases. It has various pharmacological effects such as anti-inflammatory, analgesic, and anti-tumor. As a strong histamine-releasing agent, SIN has drawn increasing attention in regards to its side effects such as allergic, gastrointestinal, and circulatory systemic reactions. In this report, we first described a patient with primary membranous nephropathy (PMN) who was treated with oral intake of SIN and developed medicine-induced toxic epidermal necrolysis (TEN) and subsequently died of septic multi-organ failure. The present case report intends to demonstrate the underestimated side effects of SIN that can eventually lead to death.© Dustri-Verlag Dr. K. Feistle.

语种：

PubmedID：

第一作者：

第一作者机构： [1]State Key Laboratory of Quality Research in Chinese Medicine, Macao University of Science and Technology, Macao, and. [2]Department of Nephropathy, Zhuhai Hospital of Integrated Chinese and Western Medicine, Zhuhai, Guangdong, China. [*1]Department of Nephropathy, Zhuhai Hospital of Integrated Chinese and Western Medicine, Zhuhai, Guangdong, China

通讯作者：

通讯机构： [1]State Key Laboratory of Quality Research in Chinese Medicine, Macao University of Science and Technology, Macao, and. [2]Department of Nephropathy, Zhuhai Hospital of Integrated Chinese and Western Medicine, Zhuhai, Guangdong, China. [*1]Department of Nephropathy, Zhuhai Hospital of Integrated Chinese and Western Medicine, Zhuhai, Guangdong, China

推荐引用方式(GB/T 7714)：

APA：

MLA：

相关文献

[1]Combination therapy (toripalimab and lenvatinib)-associated toxic epidermal necrolysis in a patient with metastatic liver cancer: A case report [2]Serum IFN-γ-inducible chemolcines CXCL9 and CXCL10 are elevated in non-immediate drug hypersensitivity reactions [3]Membranous nephropathy: Mechanistic insights and therapeutic perspectives [4]Efficacy and underlying mechanisms of sinomenine in treating rheumatoid arthritis [5]Sinomenine mitigates collagen-induced arthritis mice by inhibiting angiogenesis. [6]青藤碱微乳的制备及在大鼠体肠吸收的研究 [7]Sinomenine inhibits maturation of monocyte-derived dendritic cells through blocking activation of NF-kappa B. [8]Sinomenine down-regulates TLR4/TRAF6 expression and attenuates lipopolysaccharide-induced osteoclastogenesis and osteolysis [9]Sinomenine hydrochloride bidirectionally inhibits progression of tumor and autoimmune diseases by regulating AMPK pathway [10]Zhengqing fengtongning sustained-release tablets prevents gout flares in the process of ULT A randomized, positive control, double-blind, double-simulation, multicenter trial