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The value of shear wave elasticity and shear wave dispersion imaging to evaluate the viscoelasticity of renal parenchyma in children with glomerular diseases

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机构: [1]Department of Ultrasonography, Guangzhou Women and Children’sMedical Center, Guangzhou Medical University, No.9, Jinsui Road,Guangzhou, Guangdong, China [2]The Sixth Clinical Medical College of Guangzhou University of ChineseMedicine, Shenzhen, Guangdong, China [3]Department of Ultrasonography, Shenzhen Hospital of GuangzhouUniversity of Chinese Medicine, Shenzhen, Guangdong, China [4]Nephrology department, Guangdong Provincial Clinical Research Centerfor Child Health, Guangzhou Women and Children’s medical center,Guangzhou city, China
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关键词: Child Kidney Elasticity imaging techniques Shear wave dispersion imaging Viscoelasticity

摘要:
To study the value of shear wave elasticity and shear wave dispersion imaging to evaluate the viscoelasticity of renal parenchyma in children with glomerular diseases.Forty-three children with glomerular diseases were prospectively evaluated by shear wave elasticity (SWE) and shear wave dispersion imaging (SWD); 43 healthy volunteers served as the control group. The shear wave velocities (SWV) and the dispersion slopes were measured at the upper, middle, and lower poles of both kidneys. The analysis of mean SWV and mean dispersion slope in control and patient groups was used to further evaluate the value of SWE and SWD in the viscoelasticity of renal parenchyma in children with glomerular disease.The mean SWV in children with glomerular disease was higher than that in the healthy control group (1.61 ± 0.09 m/s vs. 1.43 ± 0.07 m/s, p < 0.001). Compared with healthy group, the mean dispersion slope in children with glomerular disease was significantly increased (13.5 ± 1.39 (m/s)/kHz vs. 12.4 ± 1.40 (m/s)/kHz, p < 0.001). Correlation analysis showed absence of correlation between the SWV and dispersion slope of occult blood, serum creatinine, 24-h urine protein, blood albumin, BMI and ROI box depth of children with glomerular disease.The present study shows that it is feasible to use SWE and SWD to evaluate the difference of viscoelasticity of the renal parenchyma between healthy children and those with glomerular disease.© 2023. BioMed Central Ltd., part of Springer Nature.

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出版当年[2022]版:
大类 | 4 区 医学
小类 | 4 区 泌尿学与肾脏学
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 泌尿学与肾脏学
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出版当年[2021]版:
Q3 UROLOGY & NEPHROLOGY
最新[2023]版:
Q2 UROLOGY & NEPHROLOGY

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第一作者机构: [1]Department of Ultrasonography, Guangzhou Women and Children’sMedical Center, Guangzhou Medical University, No.9, Jinsui Road,Guangzhou, Guangdong, China
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