机构:[1]Department of Neurosurgery, Neuroscience Center, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510310, China.[2]School of Medicine, Southeast University, Nanjing 210009, China.[3]Guangdong Second Provincial General Hospital, Guangzhou 510317, China.
Respiratory viral infections have been found to have a negative impact on neurological functions, potentially leading to significant neurological impairment. The SARS-CoV-2 virus has precipitated a worldwide pandemic, posing a substantial threat to human lives. Growing evidence suggests that SARS-CoV-2 may severely affect the CNS and respiratory system. The current prevalence of clinical neurological issues associated with SARS-CoV-2 has raised significant concerns. However, there needs to be a more comprehensive understanding of the specific pathways by which SARS-CoV-2 enters the nervous system. Based on the available evidence, this review focuses on the clinical neurological manifestations of SARS-CoV-2 and the possible mechanisms by which SARS-CoV-2 invades the brain.
基金:
Thisworkwas partially sponsored by theNationalKeyR&DProgramofChina (2022YFA1104900
and 2022YFA1104904), the Innovation Team Project (2023KCXTD007) and the Special Project in Key
Areas (2021ZDZX2011) of the Department of Education of Guangdong Province, the Natural Science
Foundation of Guangdong Province (2021A1515010013), the Guangzhou Municipal Science and Technology
Project (202201011760), and the President Foundation of the Integrated Hospital of Traditional
Chinese Medicine of Southern Medical University (1202101003).
语种:
外文
PubmedID:
中科院(CAS)分区:
出版当年[2022]版:
大类|3 区生物学
小类|3 区微生物学
最新[2025]版:
大类|2 区生物学
小类|3 区微生物学
第一作者:
第一作者机构:[1]Department of Neurosurgery, Neuroscience Center, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510310, China.[2]School of Medicine, Southeast University, Nanjing 210009, China.
通讯作者:
推荐引用方式(GB/T 7714):
Ahmed Waqas,Feng Jia,Zhang Yifan,et al.SARS-CoV-2 and Brain Health: New Challenges in the Era of the Pandemic[J].Microorganisms.2023,11(10):doi:10.3390/microorganisms11102511.
APA:
Ahmed Waqas,Feng Jia,Zhang Yifan&Chen Lukui.(2023).SARS-CoV-2 and Brain Health: New Challenges in the Era of the Pandemic.Microorganisms,11,(10)
MLA:
Ahmed Waqas,et al."SARS-CoV-2 and Brain Health: New Challenges in the Era of the Pandemic".Microorganisms 11..10(2023)