机构:[1]General Hospital of Southern Theatre Command of PLA, Guangzhou 510010, China[2]Traditional Chinese Medicine Hospital of Guangdong Province, Guangzhou 510120, China广东省中医院[3]The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405, China深圳市中医院深圳医学信息中心
A new flavonoid named saniculamin C (1), together with six known compounds (2-7), were isolated from the whole plants of Sanicula lamelligera Hance. The chemical structures were elucidated by spectroscopic and physico-chemical analyses. All isolates were evaluated for in vitro cytotoxic activities against four human cancer cell lines, HepG2, SGC-7901 gastric cancer, Hela and A-549 lung cancer. Compound 1 showed potent antiproliferative activities against SGC-7901 cells with IC50 value of 7.45 mu M. In addition, compound 6 exhibited weak antiproliferative activities against HepG2, SGC-7901, Hela cancer cells with IC50 values of 10.43, 8.24 and 15.32 mu M, respectively.
第一作者机构:[1]General Hospital of Southern Theatre Command of PLA, Guangzhou 510010, China[*1]General Hospital of Southern Theatre Command of PLA, Guangzhou 510010, China
通讯作者:
通讯机构:[1]General Hospital of Southern Theatre Command of PLA, Guangzhou 510010, China[3]The First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou 510405, China[*1]General Hospital of Southern Theatre Command of PLA, Guangzhou 510010, China[*2]General Hospital of Southern Theatre Command of PLA, Guangzhou 510010, China
推荐引用方式(GB/T 7714):
Liu Wen-Hua,Huang Dong-Hui,Gan Kao,et al.Saniculamin C, a new flavonoid from Sanicula lamelligera[J].JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH.2021,23(4):379-384.doi:10.1080/10286020.2020.1730332.
APA:
Liu, Wen-Hua,Huang, Dong-Hui,Gan, Kao&Wang, Shu-Tang.(2021).Saniculamin C, a new flavonoid from Sanicula lamelligera.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,23,(4)
MLA:
Liu, Wen-Hua,et al."Saniculamin C, a new flavonoid from Sanicula lamelligera".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 23..4(2021):379-384