机构：[1]Department of Urology, Tongji Medical School, Tongji Hospital, Huazhong University of Science and Technology,华中科技大学同济医学院附属同济医院[2]Hubei Institute of Urology, Wuhan,[3]Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou,[4]Department of Urology, Beijing Tsinghua Changgung Hospital, Beijing,[5]Department of Urology, Zhongshan Hospital, Shanghai Medical College of Fudan University, Shanghai,[6]Department of Urology, GuangDong Province Hospital of Traditional Chinese Medicine, Guangzhou,广东省中医院[7]Department of Urology, The No. 181 Hospital of the People’s Liberation Army, Guilin,[8]Department of Urology,The First Affiliated Hospital of Xinjiang Medical University, Urumqi,[9]Department of Urology, The No. 5 Hospital of the People’s Liberation Army, Yinchuan,[10]Department of Urology, Shaoyang Central Hospital, Shaoyang,[11]Department of Urology, The Third Affiliated Hospital of Chongqing Medical University, Chongqing,[12]Department of Laboratory, The People's Hospital of Xinjiang Autonomous Region, Urumqi,[13]Department of Urology, Beijing Tongren Hospital, Capital Medical University, Beijing,首都医科大学附属同仁医院[14]Department of Urology, Gaomi City Hospital of Traditional Chinese Medicine, Gaomi,[15]Department of Urology, The Second Hospital of Suzhou University Medical School, Suzhou,苏州大学附属第二医院[16]Department of Urology, Peking University People's Hospital, Beijing,[17]Department of Urology, Haikou People's Hospital, Haikou,[18]Department of Urology, The Second Hospital of Xiamen City, Xiamen,[19]Department of Urology, The First People's Hospital of Ningbo City, Ningbo University Medical School, Ningbo,[20]Department of Urology, The First Affiliated Hospital of Shihezi University Medical School, Shihezi,[21]Department of Urology, Wuxi People's Hospital of Nanjing Medical University, Wuxi,[22]Department of Urology, The First Affiliated Hospital of Medical School of Zhejiang University, Hangzhou,浙江大学医学院附属第一医院[23]Department of Urology, Xijing Hospital of the Fourth Military Medical University, Xi'an,[24]Department of Urology, The No. 113 Hospital of the People's Liberation Army, Ningbo,[25]Department of Urology, Xi'an Gaoxin Hospital, Xi'an,[26]Department of Urology, Wuhan General Hospital of Guangzhou Military Region, Wuhan,[27]Department of Urology, The First People's Hospital of Changshu City, Changshu,[28]Department of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou,[29]Department of Urology, Jiangsu Province Hospital of Traditional Chinese Medicine, Nanjing,江苏省人民医院[30]Department of Urology, The People's Hospital of Guizhou Province, Guiyang,[31]Department of Urology, The People's Hospital of Shenzhen City, Shenzhen,深圳市康宁医院深圳市人民医院深圳医学信息中心[32]Department of Urology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai,[33]Department of Urology, Taizhou Municipal Hospital, Taizhou,[34]Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang,[35]Department of Urology, The Second Affiliated Hospital of Harbin Medical University, Harbin,[36]Department of Urology, The Second Affiliated Hospital of Zhengzhou University Medical School, Zhengzhou,[37]Department of Urology, Changhai Hospital, Second Military Medical University,[38]Department of Urology, The Fifth People's Hospital of Shanghai City, Shanghai,[39]Department of Urology, Ganzhou People's Hospital, Ganzhou,[40]Department of Urology, The Second Affiliated Hospital of Tianjin Medical University, Tianjin,[41]Department of Urology, The First Affiliated Hospital of Shanxi Medical University, Taiyuan,[42]Department of Urology, The Fourth Affiliated Hospital of China Medical University, Shenyang,[43]Department of Urology, The First Hospital of Jilin University, Changchun,[44]Department of Urology, Shenyang Red-Cross Hospital, Shenyang,[45]Department of Urology, The Affiliated Hospital of Hainan Medical College, Haikou,[46]Department of Urology, The Second Hospital of Lanzhou University Medical School, Lanzhou, and[47]Department of Urology, The First Affiliated Hospital of Xiamen University, Xiamen, China
Objectives To explore characteristics of urinary stone composition in China, and determine the effects of gender, age, body mass index (BMI), stone location, and geographical region on stone composition. Patients and methods We prospectively used Fourier-transform infrared spectroscopy to analyse stones from consecutive patients presenting with new-onset urolithiasis at 46 hospitals in seven geographical areas of China, between 1 June 2010 and 31 May 2015. Chi-squared tests and logistic regression analyses were used to determine associations between stone composition and gender, age,BMI, stone location, and geographical region. Results The most common stone constituents were: calcium oxalate (CaOx; 65.9%), carbapatite (15.6%), urate (12.4%), struvite (2.7%), and brushite (1.7%). CaOx and urate stones occurred more frequently in males, whereas carbapatite and struvite were more common in females (P < 0.01). CaOx and carbapatite were more common in those aged 30-50 and 20-40 years than in other groups. Brushite and struvite were most common amongst those aged 70 years. The detection rate of urate increased with age, whilst cystine decreased with age. Obese patients were more likely to have urate stones than carbapatite or brushite stones (P < 0.01). CaOx, carbapatite, brushite, and cystine stones were more frequently found in the kidney than other types, whereas urate and struvite were more frequent in the bladder (P < 0.01). Stone composition varied by geographical region. Conclusions The most common stone composition was CaOx, followed by carbapatite, urate, struvite, and brushite. Stone composition differed significantly in patients grouped by gender, age,BMI, stone location, and geographical region.
第一作者机构：[1]Department of Urology, Tongji Medical School, Tongji Hospital, Huazhong University of Science and Technology,[2]Hubei Institute of Urology, Wuhan,
共同第一作者：
通讯作者：
通讯机构：[1]Department of Urology, Tongji Medical School, Tongji Hospital, Huazhong University of Science and Technology,[2]Hubei Institute of Urology, Wuhan,[47]Department of Urology, The First Affiliated Hospital of Xiamen University, Xiamen, China[*1]Department of Urology, The First Affiliated Hospital of Xiamen University, 55 Zhenhai Road, Siming District, Xiamen 361003, China[*2]Department of Urology, Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology, No. 1095 JieFang Avenue, Hankou, Wuhan 430030, China.
推荐引用方式(GB/T 7714)：
Zhangqun Ye,Guohua Zeng,Huan Yang,et al.The status and characteristics of urinary stone composition in China[J].BJU INTERNATIONAL.2020,125(6):801-809.doi:10.1111/bju.14765.
APA：
Zhangqun Ye,Guohua Zeng,Huan Yang,Jianxin Li,Kun Tang...&Hua Xu.(2020).The status and characteristics of urinary stone composition in China.BJU INTERNATIONAL,125,(6)
MLA：
Zhangqun Ye,et al."The status and characteristics of urinary stone composition in China".BJU INTERNATIONAL 125..6(2020):801-809
