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Predictive value of big endothelin-1 on outcomes in patients with myocardial infarction younger than 35years old

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收录情况： ◇ SCIE

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机构： [1]Division of Dyslipidemia, State Key Laboratory of Cardiovascular Disease, Fu Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, BeiLiShi Road 167, Beijing 100037, China [2]Division of Chest Pain Center, Guangdong Provincial Hospital of Chinese Medicine & The 2nd Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, China

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关键词： coronary artery disease endothelin-1 myocardial infarction outcome young

摘要：

Aim: The predictive value of big endothelin-1(ET-1) for cardiovascular outcomes in myocardial infarction (MI) patients younger than 35years old has not been characterized. Methods: A total of 565 consecutive MI patients younger than 35years old were studied and followed up for 37.78 +/- 24.9months. Results: Multivariable Cox regression analysis showed that big ET-1 was positively correlated with major adverse cardiovascular events [MACEs] (odds ratio: 3; 95% CI: 1.92-4.68; p<0.001). The area under receiver operating characteristics curve showing the predictive value of big ET-1 on MACEs was 0.67. Conclusion: The study first demonstrated that big ET-1 was an independent predictor for MACEs in MI patients younger than 35years old.

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出版当年[2017]版：

大类 | 4 区医学

小类 | 4 区药学

最新[2025]版：

大类 | 4 区医学

小类 | 4 区药学

JCR分区：

出版当年[2016]版：

Q4 PHARMACOLOGY & PHARMACY

最新[2023]版：

Q3 PHARMACOLOGY & PHARMACY

影响因子： 1.7 最新[2023版] 1.9 最新五年平均 1.01 出版当年[2016版] 1.214 出版当年五年平均 1 出版前一年[2015版] 1.032 出版后一年[2017版]

第一作者：

第一作者机构： [1]Division of Dyslipidemia, State Key Laboratory of Cardiovascular Disease, Fu Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College, BeiLiShi Road 167, Beijing 100037, China

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