机构:[1]Department of Caridiovascular, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510000, Guangdong, PR China广东省中医院[2]Dongguan Dalingshan Hospital, Dongguan, Guangdong, PR China[3]The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, PR China中山大学附属第三医院
Although some studies have investigated the association between miR-196a2 rs11614913 polymorphism and coronary artery disease (CAD) risk. The effect of miR-196a2 rs11614913 polymorphism on CAD susceptibility remain unknown. This meta-analysis aimed to determine this association. PubMed and EMBASE were searched to find relevant studies which investigated the association between miR-196a2 rs11614913 polymorphism and CAD risk. Five case-control studies including 3370 CAD patients and 3011 controls were included in this meta-analysis. MiR-196a2 rs11614913 polymorphism was not associated with CAD risk in the allelic model (OR=1.02; 95% CI 0.95-1.09; P=0.67). Additionally, no significant results were found in other genetic models. In conclusion, we found that miR-196a2 rs11614913 polymorphism played no role in CAD risk in Asians.
基金:
Traditional Chinese Medicine of Guangdong Province Hospital of Traditional Chinese Medicine [YN2014LN06]
第一作者机构:[1]Department of Caridiovascular, the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510000, Guangdong, PR China
通讯机构:[*1]Department of Caridiovascular The Second Affiliated Hospital of Guangzhou University of Chinese Medicine PR China
推荐引用方式(GB/T 7714):
Wang Xia,He Shan-Kang,Guo Wen-Hai,et al.MiR-196a2 rs11614913 polymorphism could not influence coronary artery disease risk in Asians[J].BIOMEDICAL RESEARCH-INDIA.2017,28(12):5580-5582.
APA:
Wang, Xia,He, Shan-Kang,Guo, Wen-Hai,Wu, Huan-Lin,Chen, Ya-Hui...&He, Zhi-Ling.(2017).MiR-196a2 rs11614913 polymorphism could not influence coronary artery disease risk in Asians.BIOMEDICAL RESEARCH-INDIA,28,(12)
MLA:
Wang, Xia,et al."MiR-196a2 rs11614913 polymorphism could not influence coronary artery disease risk in Asians".BIOMEDICAL RESEARCH-INDIA 28..12(2017):5580-5582