机构：[1]Key Laboratory of Laser Life Science of Ministry of Education of China, South China Normal University, Guangzhou 510631, Guangdong, China [2]Department of Anesthesiology, the Second Affiliated Clinical Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou 510120, Guangdong, China [3]Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, Guangdong, China
Here we examined the effect of human normal breast (NB) and breast cancer (BC) tissues in vitro after:treatment With glycerol in conjunction with ultrasound (surgeonperformed; SP) by OCT for functional imaging to monitor 60% glycerol (6) and SP was simultaneously, applied: for 5 min Depth - and time-resolved profiles for OCT signal enhancement were presented. The results show that OCT imaging depth of breast tissues after treatment with 60% G in combined with SP more obviously improved than that after application of glycerol alone. The permeability coefficient OP 60% glycerol in 60% G/NB 60% G/BC, 60% G/SP/NB, and 60% G/SP/BC were (0.91 +/- 0.02)x10(-5) cm/s, (3.22 +/- 0.09)x10(-5) cm/s, (1.63 +/- 0.04)x10(-5) cm/s, and (7.98 +/- 6.19)x10(-5) cm/s, respectively. The permeability coefficient of glycerol in 60% G/SP/BC was 1.84-fold than that in 60% G/NB, bin there Was 2 54-fold on permeability coefficient comparing 60% G/SP/BC with that 60% G/BC. The results from this study: indicated that the permeability coefficient of glycerol not only in normal breast tissues, but also in breast cancer tissues after treatment, with ulttrasound is larger than that in tissues without-ultrasound [GRAPHICS] The relative permeability coefficient of 60% glycerol diffusion of normal breast and breast cancer treatment With ultrasound than without ultrasound for 5 mm (C) 2010 by Astro Ltd Published exclusively by WILEY-VCH Verlag GmbH & Co KGaA
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China [60778047]; Natural Science Foundation of Guangdong ProvinceNational Natural Science Foundation of Guangdong Province [9251063101000009]; Key Science and Technology Project of Guangdong Province of China [2005B50101015, 2008B090500125]; Key Science and Technology Project of Guangzhou of China [2008Z1-D391]; Specialized Research Fund for the Doctoral Program of Higher EducationSpecialized Research Fund for the Doctoral Program of Higher Education (SRFDP) [200805740003]
第一作者机构：[1]Key Laboratory of Laser Life Science of Ministry of Education of China, South China Normal University, Guangzhou 510631, Guangdong, China
通讯作者：
推荐引用方式(GB/T 7714)：
Zhong H. Q.,Guo Z. Y.,Wei H. J.,et al.Enhancement of permeability of glycerol with ultrasound in human normal and cancer breast tissues in vitro using optical coherence tomography[J].LASER PHYSICS LETTERS.2010,7(5):388-395.doi:10.1002/lapl.201010006.
APA：
Zhong, H. Q.,Guo, Z. Y.,Wei, H. J.,Si, J. L.,Guo, L....&Liu, S. H..(2010).Enhancement of permeability of glycerol with ultrasound in human normal and cancer breast tissues in vitro using optical coherence tomography.LASER PHYSICS LETTERS,7,(5)
MLA：
Zhong, H. Q.,et al."Enhancement of permeability of glycerol with ultrasound in human normal and cancer breast tissues in vitro using optical coherence tomography".LASER PHYSICS LETTERS 7..5(2010):388-395
