详情页 - 广东省中医院知识库

当前位置：首页 > 详情页

Transcription Factors in Amphioxus

文献详情

资源类型：

作者：

机构： [a]Sun Yat-sen University, Guangzhou, China [b]DiaSys Diagnostic Systems Greater China, Shanghai, China [c]Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China [d]Guangdong Provincial Hospital of Traditional Chinese Medicine

出处：

DOI：

关键词： Amphioxus Antiviral BbeSTATa BbeSTATb BbtIRF1 BbtIRF3 BbtIRF7 Bbtp105 BbtRel DBD Evolution IFN IκB JAK NFκB P58 RHD Ubiquitination

摘要：

This chapter introduces the immune-related transcription factors in amphioxus, including NFκB, IRFs, and STATs. It starts by introducing the architecture, evolution, and transcriptional mechanism of two amphioxus NFκB family members. It then introduces the phylogeny and transcriptional activities of nine amphioxus IRFs, which shed light on the evolution of IFN-based antiviral mechanisms. By the end of the chapter the JAK. JAK-STAT pathway among species and introduction of the amphioxus STAT family are compared. The composition of transcriptional factors in amphioxus remains in a simple form compared with the great expansion in pattern recognition receptors and their adaptors, suggesting a tight regulation of amphioxus innate immune signaling at the transcriptional level. © 2016 China Science Publishing & Media Ltd. Published by Elsevier Inc.

语种：

第一作者：

第一作者机构： [a]Sun Yat-sen University, Guangzhou, China

推荐引用方式(GB/T 7714)：

APA：

MLA：

相关文献

[1]Amphioxus as a Model for Understanding the Evolution of Vertebrates [2]Primitive Adaptive Immune System of Amphioxus [3]Fufang Luohanguo Qingfei granules reduces influenza virus susceptibility via MAVS-dependent type I interferon antiviral signaling [4]Chordate PIAS proteins act as conserved repressors of the TRAF6 self-polyubiquitination [5]Three amphioxus reference genomes reveal gene and chromosome evolution of chordates [6]Elucidating the role of ubiquitination and deubiquitination in osteoarthritis progression [7]监测SARS病人IFN-γ、IFN-α、NO和iNOS水平及其意义 [8]2493例RhD阴性献血者的基因分析及4个新RHD等位基因的鉴定 [9]RHAG 236G＞A突变致Rhmod的分子背景研究及家系调查 [10]RhD抗体ssDNA适配体结构分析

日	一	二	三	四	五	六

今天

清空