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Animal exercise studies in cardiovascular research: Current knowledge and optimal design-A position paper of the Committee on Cardiac Rehabilitation, Chinese Medical Doctors' Association.

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收录情况： ◇ SCIE ◇ SSCI ◇ 卓越：重点期刊

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机构： [1]Institute of Geriatrics, Affiliated Nantong Hospital of Shanghai University, Sixth People's Hospital of Nantong, School of Medicine, Shanghai University, Nantong, 226011, China; Cardiac Regeneration and Ageing Lab, Institute of Cardiovascular Sciences, Shanghai Engineering Research Center of Organ Repair, School of Life Science, Shanghai University, Shanghai, 200444, China. [2]Department of Rehabilitation Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. [3]Department of Cardiology, Peking University People's Hospital, Beijing, 100044, China. [4]Department of Cardiology, Tongji Hospital Affiliated to Tongji University, Tongji University School of Medicine, Shanghai, 200065, China. [5]Department of Cardiology, Daqing Oilfield General Hospital, Daqing, 163000, China. [6]Department of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing Key Laboratory of Cardiovascular Receptors Research, Beijing, 100191, China. [7]Department of Rehabilitation Medicine, First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, China. [8]School of Medicine, Huaqiao University, Quanzhou, 362021, China. [9]Division of Cardiac Rehabilitation, Department of Physical Medicine and Rehabilitation, Xiangya Hospital of Central South University, Changsha, 410008, China. [10]Department of Rehabilitation Medicine, First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China. [11]Department of Cardiology, Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, 518033, China; Guangdong Innovative Engineering and Technology Research Center for Assisted Circulation, Sun Yat-sen University, Shenzhen, 518033, China; NHC Key Laboratory of Assisted Circulation, Sun Yat-sen University, Guangzhou, 510080, China. [12]Department of Rehabilitation Medicine, Shanghai Xuhui Central Hospital, Shanghai, 200031, China. [13]Cardiac Rehabilitation Department, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China. [14]Cardiac Rehabilitation Department, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, China. Electronic address: guolan1993@126.com. [15]Institute of Geriatrics, Affiliated Nantong Hospital of Shanghai University, Sixth People's Hospital of Nantong, School of Medicine, Shanghai University, Nantong, 226011, China; Cardiac Regeneration and Ageing Lab, Institute of Cardiovascular Sciences, Shanghai Engineering Research Center of Organ Repair, School of Life Science, Shanghai University, Shanghai, 200444, China. Electronic address: junjiexiao@shu.edu.cn.

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关键词： Animal studies Cardiovascular disease Cardiovascular research Exercise Exercise models

摘要：

Growing evidence has demonstrated exercise as an effective way to promote cardiovascular health and protect against cardiovascular diseases (CVDs). However, the underlying mechanisms of the beneficial effects of exercise have yet to be elucidated. Animal exercise studies are widely used to investigate the key mechanisms of exercise-induced cardiovascular protection. However, standardized procedures and well-established evaluation indicators for animal exercise models are needed to guide researchers in carrying out effective, high-quality animal studies using exercise to prevent and treat CVDs. In our review, we present the commonly used animal exercise models in cardiovascular research and propose a set of standard procedures for exercise training, emphasizing the appropriate measurements and analysis in these chronic exercise models. We also provide recommendations for optimal design of animal exercise studies in cardiovascular research, including the choice of exercise models, control of exercise protocols, exercise at different stages of disease, and other considerations such as age, sex, and genetic background. We hope that this position paper will promote basic research on exercise-induced cardiovascular protection and pave the way for successful translation of exercise studies from bench to bedside in the prevention and treatment of CVDs.Copyright © 2021. Production and hosting by Elsevier B.V.

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出版当年[2020]版：

大类 | 1 区

医学

小类 | 1 区运动科学

最新[2025]版：

大类 | 1 区

医学

小类 | 1 区酒店、休闲、体育与旅游 1 区运动科学

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出版当年[2019]版：

Q1 HOSPITALITY, LEISURE, SPORT & TOURISM Q1 SPORT SCIENCES

最新[2023]版：

Q1 HOSPITALITY, LEISURE, SPORT & TOURISM Q1 SPORT SCIENCES

影响因子： 9.7 最新[2023版] 9.2 最新五年平均 5.2 出版当年[2019版] 4.687 出版当年五年平均 3.644 出版前一年[2018版] 7.179 出版后一年[2020版]

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Animal exercise studies in cardiovascular research: Current knowledge and optimal design-A position paper of the Committee on Cardiac Rehabilitation, Chinese Medical Doctors' Association.

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