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Cognitive impairment in patients with heart failure: molecular mechanism and therapy

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机构: [1]South China Univ Technol, Sch Med, Dept Anesthesiol, Guangzhou 510006, Peoples R China [2]Capital Med Univ, Beijing Anzhen Hosp, Dept Anesthesiol, Beijing, Peoples R China [3]Guangdong Acad Med Sci, Guangdong Prov Peoples Hosp, Dept Anesthesiol, Guangzhou, Guangdong, Peoples R China [4]Jinan Univ, Dept Anesthesiol, Affiliated Hosp 1, Guangzhou 510630, Guangdong, Peoples R China [5]Guangzhou Univ Chinese Med, Dept Neurol, Affiliated Hosp 2, Guangzhou, Peoples R China
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关键词: Heart failure Cognitive impairment Pathophysiological mechanism Treatment Nursing

摘要:
Heart failure (HF) is associated with multiple organ dysfunction and many comorbidities. Its incidence is high among the elderly and is a major health burden worldwide. Cognitive impairment (CI) is highly prevalent in older patients with HF, which is an abnormality in one or more of the items of cognition, attention, memory, language, psychomotor function, and visual spatial acuity. Studies have shown that the incidence of CI in HF patients is between 13 and 54%, and patients with both conditions have poor self-care ability and prognosis, as well as increased mortality rates. However, the mechanisms of CI development in HF patients are still unclear. In this review, we describe the epidemiology and risk factors as well as measures of improving CI in HF patients. We update the latest pathophysiological mechanisms related to the neurocognitive changes in HF patients, expounding on the mechanisms associated with the development of CI in HF patients.

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出版当年[2022]版
大类 | 2 区 医学
小类 | 3 区 心脏和心血管系统
最新[2025]版
大类 | 2 区 医学
小类 | 3 区 心脏和心血管系统
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出版当年[2021]版:
Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
最新[2023]版:
Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

影响因子: 最新[2023版] 最新五年平均 出版当年[2021版] 出版当年五年平均 出版前一年[2020版] 出版后一年[2022版]

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第一作者机构: [1]South China Univ Technol, Sch Med, Dept Anesthesiol, Guangzhou 510006, Peoples R China [3]Guangdong Acad Med Sci, Guangdong Prov Peoples Hosp, Dept Anesthesiol, Guangzhou, Guangdong, Peoples R China
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通讯机构: [1]South China Univ Technol, Sch Med, Dept Anesthesiol, Guangzhou 510006, Peoples R China [2]Capital Med Univ, Beijing Anzhen Hosp, Dept Anesthesiol, Beijing, Peoples R China [3]Guangdong Acad Med Sci, Guangdong Prov Peoples Hosp, Dept Anesthesiol, Guangzhou, Guangdong, Peoples R China
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