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Developing and predicting of early mortality after endovascular thrombectomy in patients with acute ischemic stroke

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资源类型：
Pubmed体系：
作者：
Yimin Chen[1] * ; Sijie Zhou[2] ; Shuiquan Yang[1] ; Mohammad Mofatteh[3] ; Yuqian Hu[4] ; Hongquan Wei[5] ; Yuzheng Lai[6] ; Zhiyi Zeng[7] ; Yajie Yang[8] ; Junlin Yu[9] ; Juanmei Chen[10] ; Xi Sun[11,12] ; Wenlong Wei[1] ; Thanh N. Nguyen[13] ; José Fidel Baizabal-Carvallo[14,15] ; Xuxing Liao[2,16] ;
机构： [1]Department of Neurology and Advanced National Stroke Center, Foshan Sanshui District People's Hospital, Foshan, Guangdong, China. [2]Department of Surgery of Cerebrovascular Diseases, The First People's Hospital of Foshan, Foshan, Guangdong, China. [3]School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom. [4]The First School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China. [5]Department of 120 Emergency Command Center, Foshan Sanshui District People's Hospital, Foshan, Guangdong, China. [6]Department of Neurology, Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Nanhai District Hospital of Traditional Chinese Medicine of Foshan City, Foshan, Guangdong, China. [7]Department of Scientific Research and Education, Foshan Sanshui District People's Hospital, Foshan, Guangdong, China. [8]The First School of Clinical Medicine, Southern Medical University, Foshan, China. [9]School of Laboratory Medicine and Biotechnology, Southern Medical University, Foshan, China. [10]Second Clinical College, Guangzhou Medical University, Guangzhou, China. [11]School of Medicine, Shaoguan University, Shaoguan, Guangdong, China. [12]Medical Intern, Foshan Sanshui District People's Hospital, Foshan, Guangdong, China. [13]Department of Neurology, Radiology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, United States. [14]Department of Neurology, Baylor College of Medicine, Parkinson's Disease Center and Movement Disorders Clinic, Houston, TX, United States. [15]Department of Sciences and Engineering, University of Guanajuato, León, Mexico [16]Department of Neurosurgery and Advanced National Stroke Center, Foshan Sanshui District People's Hospital, Foshan, Guangdong, China.
出处：
DOI： 10.3389/fnins.2022.1034472
ISSN：

关键词： ischemic stroke endovascular therapy thrombectomy intracranial hemorrhage mortality

摘要：
Stroke is one of the leading causes of mortality across the world. However, there is a paucity of information regarding mortality rates and associated risk factors in patients with acute ischemic stroke (AIS) undergoing endovascular thrombectomy (EVT). In this study, we aimed to clarify these issues and analyzed previous publications related to mortality in patients treated with EVT.We analyzed the survival of 245 consecutive patients treated with mechanical thrombectomy for AIS for which mortality information was obtained. Early mortality was defined as death occurring during hospitalization after EVT or within 7 days following hospital discharge from the stroke event.Early mortality occurred in 22.8% of cases in this cohort. Recanalization status (modified thrombolysis in cerebral infarction, mTICI) (p = 0.002), National Institute of Health Stroke Scale Score (NIHSS) score 24-h after EVT (p < 0.001) and symptomatic intracerebral hemorrhage (sICH) (p < 0.001) were independently associated with early mortality. Age, sex, cardiovascular risk factors, NIHSS score pre-treatment, Alberta Stroke Program Early CT Score (ASPECTS), stroke subtype, site of arterial occlusion and timing form onset to recanalization did not have an independent influence on survival. Non-survivors had a shorter hospitalization (p < 0.001) but higher costs related to their hospitalization and outpatient care.The recanalization status, NIHSS score 24-h after EVT and sICH were predictors of early mortality in AIS patients treated with EVT.Copyright © 2022 Chen, Zhou, Yang, Mofatteh, Hu, Wei, Lai, Zeng, Yang, Yu, Chen, Sun, Wei, Nguyen, Baizabal-Carvallo and Liao.

基金：
This study was supported by Foshan 14th Five-Year Plan Key Discipline Foundation, China, the Guangdong Provincial TCM Bureau Key Discipline Foundation, China, and Foshan Competitive Talent Support Project Fund (Brain-Heart Talent Project-Build the Brain-Heart Comorbidity Muti-disciplinary Medical Center).
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2021]版：
大类 | 3 区 医学
小类 | 3 区 神经科学
最新[2025]版：
大类 | 3 区 医学
小类 | 3 区 神经科学
第一作者：
第一作者机构： [1]Department of Neurology and Advanced National Stroke Center, Foshan Sanshui District People's Hospital, Foshan, Guangdong, China.
通讯作者：
通讯机构： [2]Department of Surgery of Cerebrovascular Diseases, The First People's Hospital of Foshan, Foshan, Guangdong, China. [14]Department of Neurology, Baylor College of Medicine, Parkinson's Disease Center and Movement Disorders Clinic, Houston, TX, United States. [15]Department of Sciences and Engineering, University of Guanajuato, León, Mexico [16]Department of Neurosurgery and Advanced National Stroke Center, Foshan Sanshui District People's Hospital, Foshan, Guangdong, China.
推荐引用方式(GB/T 7714)：
Yimin Chen,Sijie Zhou,Shuiquan Yang,et al.Developing and predicting of early mortality after endovascular thrombectomy in patients with acute ischemic stroke[J].Frontiers in neuroscience.2022,16:1034472.doi:10.3389/fnins.2022.1034472.
APA：
Yimin Chen,Sijie Zhou,Shuiquan Yang,Mohammad Mofatteh,Yuqian Hu...&Xuxing Liao.(2022).Developing and predicting of early mortality after endovascular thrombectomy in patients with acute ischemic stroke.Frontiers in neuroscience,16,
MLA：
Yimin Chen,et al."Developing and predicting of early mortality after endovascular thrombectomy in patients with acute ischemic stroke".Frontiers in neuroscience 16.(2022):1034472

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[1]7-Day National Institutes of Health Stroke Scale as a surrogate marker predicting ischemic stroke patients' outcome following endovascular therapy [2]Association of Early Increase in Body Temperature with Symptomatic Intracranial Hemorrhage and Unfavorable Outcome Following Endovascular Therapy in Patients with Large Vessel Occlusion Stroke [3]Crossover from Femoral to Radial Access during Mechanical Thrombectomy of Large Vessel Occlusion Stroke [4]Trial of Endovascular Therapy for Acute Ischemic Stroke with Large Infarct [5]Predictors of failure of early neurological improvement in early time window following endovascular thrombectomy: a multi-center study [6]Effect of atrial fibrillation on outcomes in patients with anterior circulation occlusion stroke receiving endovascular therapy [7]Milky Layered Cerebrospinal Fluid in Intracranial Hemorrhage. [8]Predictors of futile recanalization after endovascular treatment in acute ischemic stroke: a multi-center study [9]Efficacy and Safety of a Novel Thrombectomy Device in Patients With Acute Ischemic Stroke: A Randomized Controlled Trial [10]Association of Prophylactic Use of Stress Ulcer Drugs and Clinical Outcomes in Patients With Acute Anterior Circulation Thrombectomy

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