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Novel nano-drug delivery system for natural products and their application

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机构： [1]State Key Laboratory of Quality Research in Chinese Medicines, Macau University of Science and Technology, Macau, China. [2]State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.

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关键词： Natural products Novel nano-drug delivery system Bioavailability Therapeutic effects

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The development of natural products for potential new drugs faces obstacles such as unknown mechanisms, poor solubility, and limited bioavailability, which limit the broadened applicability of natural products. Therefore, there is a need for advanced pharmaceutical formulations of active compounds or natural products. In recent years, novel nano-drug delivery systems (NDDS) for natural products, including nanosuspensions, nanoliposomes, micelle, microemulsions/self-microemulsions, nanocapsules, and solid lipid nanoparticles, have been developed to improve solubility, bioavailability, and tissue distribution as well as for prolonged retention and enhanced permeation. Here, we updated the NDDS delivery systems used for natural products with the potential enhancement in therapeutic efficiency observed with nano-delivery systems.Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.

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出版当年[2023]版：

大类 | 2 区

医学

小类 | 1 区药学

最新[2025]版：

大类 | 2 区

医学

小类 | 1 区药学

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第一作者机构： [1]State Key Laboratory of Quality Research in Chinese Medicines, Macau University of Science and Technology, Macau, China.

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Novel nano-drug delivery system for natural products and their application