机构：[a]The Fifth Clinical Medical School, Guangzhou University of Chinese Medicine,[b]Guangdong Second Traditional Chinese Medicine Hospital,[c]Guangdong Provincial Key Laboratory of Research and Development in Traditional Chinese Medicine, Guangdong Province Engineering Technology Research Institute of Traditional Chinese Medicine, Guangzhou, Guangdong, P.R. China.
Knee osteoarthritis (KOA) is a common progressive joint disorder in old people. Bushen huoxue (BSHX) is a classical method of TCM in treating KOA. However, there is no systematic review related to BSHX for KOA. The purpose of this study is to provide a comprehensive and reliable evaluation of the clinical evidence of BSHX in the treatment of KOA.
We searched relevant studies on BSHX for KOA from the databases of PubMed, Embase, MEDLINE, Cochrane Library Central Register of Controlled Trials, China national knowledge infrastructure database (CNKI), Wan fang database, Chongqing VIP information, and SinoMed from their inception to May 2020. Two researchers will select and evaluate qualified studies independently. The primary outcomes of this review will focus on pain intensity. The meta-analyses will be performed by using the RevMan 5.3.
The study will provide a comprehensive evaluation of the efficacy and safety of the BSHX method for patients with KOA.
The results of this systematic review will provide evidence to judge whether BSHX is an effective intervention for patients with KOA.
基金：
This work was supported by Guangdong Province famous Chinese medicine heritage studio construction project (Guangdong Traditional Chinese Medicine Office
Letter [F2017] 17); Guangdong Provincial Special Fund for Industrial and Information Development (Guangdong Finance and Industry [2016] 69); Natural Science
Foundation of Guangdong Province (No.2018A030313584); Administration of Traditional Chinese Medicine of Guangdong Province (No.20183001); Guangdong
Provincial Soft Science Research Project (No.2018B020207009), and by Science and Technology Planning Project of Guangdong Province (No.2019A141401008).
语种：
外文
PubmedID：
中科院(CAS)分区：
出版当年[2019]版：
大类|4 区医学
小类|3 区医学：内科
最新[2025]版：
大类|4 区医学
小类|4 区医学：内科
第一作者：
第一作者机构：[a]The Fifth Clinical Medical School, Guangzhou University of Chinese Medicine,
共同第一作者：
通讯作者：
通讯机构：[a]The Fifth Clinical Medical School, Guangzhou University of Chinese Medicine,[b]Guangdong Second Traditional Chinese Medicine Hospital,[*1]Orthopedics Department, Guangdong Second Traditional Chinese Medicine Hospital, 60 Hengfu Road, Guangzhou, Guangdong 510095, P.R. China
推荐引用方式(GB/T 7714)：
Guocai Chen,Xiangling Ye,Yingxin Guan,et al.Effects of bushen huoxue method for knee osteoarthritis: A protocol for systematic review and meta-analysis.[J].Medicine.2020,99(24):e20659.doi:10.1097/MD.0000000000020659.
APA：
Guocai Chen,Xiangling Ye,Yingxin Guan,Wengang Liu,Jianping Du...&Xuemeng Xu.(2020).Effects of bushen huoxue method for knee osteoarthritis: A protocol for systematic review and meta-analysis..Medicine,99,(24)
MLA：
Guocai Chen,et al."Effects of bushen huoxue method for knee osteoarthritis: A protocol for systematic review and meta-analysis.".Medicine 99..24(2020):e20659
