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Biomedical Application of Reactive Oxygen Species-Responsive Nanocarriers in Cancer, Inflammation, and Neurodegenerative Diseases

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收录情况： ◇ SCIE

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机构： [1]Orthopedics Department, Guangdong Provincial Hospital of Traditional Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China [2]Department of Chemistry, Jinan University, Guangzhou, China

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关键词： cancer inflammation nanocarriers neurodegenerative diseases reactive oxygen species

摘要：

Numerous pathological conditions, including cancer, inflammatory diseases, and neurodegenerative diseases, are accompanied by overproduction of reactive oxygen species (ROS). This makes ROS vital flagging molecules in disease pathology. ROS-responsive drug delivery platforms have been developed. Nanotechnology has been broadly applied in the field of biomedicine leading to the progress of ROS-responsive nanoparticles. In this review, we focused on the production and physiological/pathophysiological impact of ROS. Particular emphasis is put on the mechanisms and effects of abnormal ROS levels on oxidative stress diseases, including cancer, inflammatory disease, and neurodegenerative diseases. Finally, we summarized the potential biomedical applications of ROS-responsive nanocarriers in these oxidative stress diseases. We provide insights that will help in the designing of new ROS-responsive nanocarriers for various applications. © Copyright © 2020 Liu, Li, Chen, Lin, Lai, Chen and Chen.

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出版当年[2019]版：

大类 | 2 区化学

小类 | 3 区化学综合

最新[2025]版：

大类 | 3 区化学

小类 | 4 区化学：综合

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出版当年[2018]版：

Q2 CHEMISTRY, MULTIDISCIPLINARY

最新[2023]版：

Q2 CHEMISTRY, MULTIDISCIPLINARY

影响因子： 3.8 最新[2023版] 4.8 最新五年平均 3.782 出版当年[2018版] 4.714 出版当年五年平均 4.155 出版前一年[2017版] 3.693 出版后一年[2019版]

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第一作者机构： [1]Orthopedics Department, Guangdong Provincial Hospital of Traditional Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China

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