机构:[a]Guangzhou University of Chinese Medicine,The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of China.[b]First Affiliated Hospital of Guangdong Pharmaceutical University,The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of China.[c]Department of Acupuncture, The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of China.
Herpes zoster (HZ) is currently treated primarily with antiviral drugs, yet this treatment has been debated. Acupuncture is becoming a more important treatment in this protocol. For example, pain intensity is lower among HZ patients who receive acupuncture plus moxibustion than among those who receive pharmacotherapy. There are many types of acupuncture interventions, including electroacupuncture, moxibustion, bloodletting. In this study, a network meta-analysis (NMA) is used to rank various interventions of acupuncture.
Electronic searches of abstracts and titles will be performed in MEDLINE, EMBASE, CENTRAL, CBM, CNKI, CQVIP, and Wanfang Data databases, from inception to December 31, 2019. Published and unpublished controlled trials with different acupuncture interventions will be selected, trials of antiviral drugs as the control group. All patients of HZ will be included, except for those diagnosed with PHN, immunocompromised patients, or those with complications. The effective therapy rate and the incidence of PHN are primary outcomes. The NMA will be analyzed with Stata 13.0 and GeMTC 0.14.3.
The NMA will be established to compare various interventions of acupuncture for the therapy of HZ, that could resolve the limitations of previous methodologies with this protocol. It will be possible to determine the best acupuncture intervention for more primary outcomes of therapy, including subgroup analysis of patients with aged ≥50 years and those of aged <50 years.
The NMA does not require ethical approval. The data analyzed is not personal. It is only systematically used to evaluate the effectiveness of acupuncture treatments. The results will be disseminated through international conference reports and peer-reviewed manuscripts.
A comprehensive methodology is established to rank various interventions of acupuncture by which best evidence-based intervention may be recommended for those population groups of aged ≥50 years and aged <50 years.
CRD42019118369.
基金:
This research was supported by the Natural Science Foundation of China (grant No. 81574061), and the Guangdong Science and Technology Commission Foundation
(No. 2017A020213019). The funders did not play any role in the study design, the data collection the preparation of the manuscript, or the decision to publish.
语种:
外文
PubmedID:
中科院(CAS)分区:
出版当年[2019]版:
大类|4 区医学
小类|3 区医学:内科
最新[2025]版:
大类|4 区医学
小类|4 区医学:内科
第一作者:
第一作者机构:[a]Guangzhou University of Chinese Medicine,The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of China.
通讯作者:
通讯机构:[c]Department of Acupuncture, The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, People’s Republic of China.[*1]Department of Acupuncture, The First Affiliated Hospital, Guangzhou University of Chinese Medicine, No.16 Airport Road, Baiyun District, Guangzhou, 510405, People’s Republic of China
推荐引用方式(GB/T 7714):
Na Zhang,Kun Liu,Yalin She,et al.Efficacy and safety of acupuncture and moxibustion for herpes zoster: A protocol for systematic review and network meta analysis.[J].Medicine.2020,99(36):e21905.doi:10.1097/MD.0000000000021905.
APA:
Na Zhang,Kun Liu,Yalin She,Weixuan Zhao,Jingchun Zeng&Guohua Lin.(2020).Efficacy and safety of acupuncture and moxibustion for herpes zoster: A protocol for systematic review and network meta analysis..Medicine,99,(36)
MLA:
Na Zhang,et al."Efficacy and safety of acupuncture and moxibustion for herpes zoster: A protocol for systematic review and network meta analysis.".Medicine 99..36(2020):e21905