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Two new saponins from Thalictrum fortunei

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机构: [a]Guangdong Research Institute of Traditional Chinese Medicine, Guangzhou 510520, China [b]Department of Pharmacy Engineering, Institute of Chemistry and Chemical Engineering, Qiqihar University, Qiqihar 16100, China [c]Institute of Chinese Medical Sciences, University of Macau, Taipa, Macau China
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关键词: Cycloartane glycoside Cytotoxic Ranunculaceae Thalictrum fortunei

摘要:
Two new cycloartane glycosides were isolated from the aerial parts of Thalictrum fortunei (Ranunculaceae). The chemical structures of these compounds were elucidated as 3-O-β-D-glucopyranosyl (1 → 4)-β-D- fucopyranosyl-(22S,24Z)-cycloart-24-en-3β,22,26,30-tetraol 26-O-β-D-glucopyranoside and 3-O-β-D-glucopyranosyl (1 → 4)-b-D-fucopyranosyl-(22S,24Z)-cycloart-24-en-3β,22,26,29-tetraol 26-O-β-Dglucopyranoside by extensive 1D and 2D NMR methods, HR-ESI-MS, and hydrolysis. Their cytotoxic activities toward human hepatoma Bel-7402 cells, human colon carcinoma LoVo cells, and human non-small-cell lung cancer NCIH-460 cells were evaluated by MTT assay, respectively. © 2012 Taylor & Francis.

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出版当年[2011]版:
大类 | 4 区 医学
小类 | 4 区 应用化学 4 区 药物化学 4 区 药学 4 区 植物科学
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 应用化学 4 区 药物化学 4 区 药学 4 区 植物科学
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