详情页 - 广东省中医院知识库

当前位置：首页 > 详情页

Highly oxygenated ent-atisane and podocarpane diterpenoids from Excoecaria agallocha

10| 认领 | 导出 | 链接全文 |

文献详情

资源类型：

WOS体系：

Pubmed体系：

收录情况： ◇ SCIE

作者：

机构： [1]Guangxi Key Laboratory of New Energy and Building Energy Saving, Guilin University of Technology, Guilin, China [2]College of Civil and Architecture Engineering, Guilin University of Technology, Guilin, China [3]School of Intelligent Manufacturing, Panzhihua University, Panzhihua, China [4]Department of Cardiovascular Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China [5]State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China

出处：

DOI：

ISSN：

关键词： Excoecaria agallocha entatisane diterpenoid podocarpane diterpenoid cytotoxicity

摘要：

A new highly oxygenated ent-atisane diterpenoid, namely excagallonoid A (1), together with five known analogues (2 − 6) were isolated from the leaves and twigs of Excoecaria agallocha. Their structures were elucidated on the basis of extensive spectroscopic analyses (HRESIMS, UV, IR, 1 D and 2 D NMR), and the absolute configurations of 1 and 5 were determined by single-crystal X-ray diffraction. Compound 1 represents the first example of an ent-atisane diterpenoid featuring a vicinal 2,3-diol moiety. Compounds 1 and 4 exhibited weak cytotoxicities in vitro against RKO colon cancer cells with IC50 values of 28.7 ± 1.98 and 32.6 ± 2.81 µM, respectively. © 2021 Informa UK Limited, trading as Taylor & Francis Group.

语种：

WOS：

PubmedID：

中科院(CAS)分区：

出版当年[2021]版：

大类 | 3 区化学

小类 | 3 区应用化学 3 区药物化学

最新[2025]版：

大类 | 3 区化学

小类 | 3 区应用化学 4 区药物化学

JCR分区：

出版当年[2020]版：

Q2 CHEMISTRY, APPLIED Q3 CHEMISTRY, MEDICINAL

最新[2023]版：

Q3 CHEMISTRY, APPLIED Q3 CHEMISTRY, MEDICINAL

影响因子： 1.9 最新[2023版] 2.1 最新五年平均 2.862 出版当年[2020版] 2.572 出版当年五年平均 2.158 出版前一年[2019版] 2.488 出版后一年[2021版]

第一作者：

第一作者机构： [1]Guangxi Key Laboratory of New Energy and Building Energy Saving, Guilin University of Technology, Guilin, China [2]College of Civil and Architecture Engineering, Guilin University of Technology, Guilin, China

通讯作者：

通讯机构： [1]Guangxi Key Laboratory of New Energy and Building Energy Saving, Guilin University of Technology, Guilin, China [2]College of Civil and Architecture Engineering, Guilin University of Technology, Guilin, China [4]Department of Cardiovascular Medicine, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, China [5]State Key Laboratory of Dampness Syndrome of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China

推荐引用方式(GB/T 7714)：

APA：

MLA：

Highly oxygenated ent-atisane and podocarpane diterpenoids from Excoecaria agallocha

文献详情

相关文献